TY - JOUR
T1 - Intolerance of Uncertainty Predicts Anxiety Outcomes Following CBT in Youth with ASD
AU - Keefer, Amy
AU - Kreiser, Nicole L.
AU - Singh, Vini
AU - Blakeley-Smith, Audrey
AU - Duncan, Amie
AU - Johnson, Catherine
AU - Klinger, Laura
AU - Meyer, Allison
AU - Reaven, Judy
AU - Vasa, Roma A.
N1 - Funding Information:
Drs. Reaven, Keefer, Duncan, and Klinger and Ms. Johnson were supported by NIH Grant 4R33MH089291-03 which was awarded to Dr. Reaven. Recruitment at TEACCH Autism Program was supported by NICHD Grant U54HD079124. Dr. Vasa’s effort was supported by Autism Speaks Grant 8790. This study was funded in part by NIH Grant #4R33MH089291-03, Autism Speaks Grant #8790, and NICHD Grant #U54HD079124. AK conceived of the study, participated in its design and coordination, and drafted the manuscript; NK participated in the design and interpretation of the data and drafting the manuscript; VS participated in the design and performed the statistical analysis; ABS participated in drafting the manuscript; AD participated in the measurement and drafting the manuscript; CJ participated in the measurement and design; LK participated in drafting the manuscript; AM participated in the measurement and drafting the manuscript; JR contributed to the interpretation of the data and drafting the manuscript; RV conceived of the study, participated in its design and drafting the manuscript. All authors read and approved the final manuscript. Drs. Keefer, Kreiser, Duncan, Klinger, Meyer, and Vasa and Ms. Johnson and Ms. Singh have no conflicts of interest. Drs. Reaven and Blakeley-Smith receive royalties from Paul H. Brookes, publisher of the Facing Your Fears treatment manual.
Funding Information:
Acknowledgments Drs. Reaven, Keefer, Duncan, and Klinger and Ms. Johnson were supported by NIH Grant 4R33MH089291-03 which was awarded to Dr. Reaven. Recruitment at TEACCH Autism Program was supported by NICHD Grant U54HD079124. Dr. Vasa’s effort was supported by Autism Speaks Grant 8790.
Funding Information:
Funding This study was funded in part by NIH Grant #4R33MH089291-03, Autism Speaks Grant #8790, and NICHD Grant #U54HD079124.
Publisher Copyright:
© 2016, Springer Science+Business Media New York.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Modified cognitive–behavioral therapy (MCBT) has been demonstrated to reduce anxiety in youth with autism spectrum disorder (ASD). However, non-response rates are fairly high. Few studies have investigated factors associated with response. Intolerance of uncertainty (IU) is a treatment target for anxiety and worry in neurotypical populations and has been linked to anxiety and ASD. We sought to examine whether IU affects outcomes following MCBT in 43 children, ages 8–14 years, with ASD without intellectual disability. Consistent with prior data, there was a significant reduction in parent reported anxiety following MCBT. Higher levels of pre-intervention IU predicted higher anxiety and worry pre- and post-intervention. These findings suggest that targeting IU may improve outcomes following MCBT in youth with ASD and anxiety.
AB - Modified cognitive–behavioral therapy (MCBT) has been demonstrated to reduce anxiety in youth with autism spectrum disorder (ASD). However, non-response rates are fairly high. Few studies have investigated factors associated with response. Intolerance of uncertainty (IU) is a treatment target for anxiety and worry in neurotypical populations and has been linked to anxiety and ASD. We sought to examine whether IU affects outcomes following MCBT in 43 children, ages 8–14 years, with ASD without intellectual disability. Consistent with prior data, there was a significant reduction in parent reported anxiety following MCBT. Higher levels of pre-intervention IU predicted higher anxiety and worry pre- and post-intervention. These findings suggest that targeting IU may improve outcomes following MCBT in youth with ASD and anxiety.
KW - Anxiety
KW - Autism spectrum disorders
KW - Cognitive–behavioral therapy
KW - Intolerance of uncertainty
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UR - http://www.scopus.com/inward/citedby.url?scp=84978152170&partnerID=8YFLogxK
U2 - 10.1007/s10803-016-2852-z
DO - 10.1007/s10803-016-2852-z
M3 - Article
C2 - 27405445
AN - SCOPUS:84978152170
SN - 0162-3257
VL - 47
SP - 3949
EP - 3958
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 12
ER -