Intimate partner violence is associated with incident HIV infection in women in Uganda

Fiona G. Kouyoumdjian, Liviana M. Calzavara, Susan J. Bondy, Patricia O'Campo, David Serwadda, Fred Nalugoda, Joseph Kagaayi, Godfrey Kigozi, Maria J Wawer, Ronald H Gray

Research output: Contribution to journalArticle

Abstract

Objectives: To quantify the association between intimate partner violence (IPV) and incident HIV infection in women in the Rakai Community Cohort Study between 2000 and 2009. Design and methods: Data were from the Rakai Community Cohort Study annual surveys between 2000 and 2009. Longitudinal data analysis was used to estimate the adjusted incidence rate ratio (IRR) of incident HIV associated with IPV in sexually active women aged 15-49 years, using a multivariable Poisson regression model with random effects. The population attributable fraction was calculated. Putative mediators were assessed using Baron and Kenny's criteria and the Sobel-Goodman test. Results: Women who had ever experienced IPV had an adjusted IRR of incident HIV infection of 1.55 (95% CI1.25-1.94, P = 0.000), compared with women who had never experienced IPV. Risk of HIV infection tended to be greater for longer duration of IPV exposure and for women exposed to more severe and more frequent IPV. The adjusted population attributable fraction of incident HIV attributable to IPV was 22.2% (95% CI 12.5-30.4). There was no evidence that either condom use or number of sex partners in the past year mediated the relationship between IPV and HIV. Conclusion: IPV is associated with incident HIV infection in a population-based cohort in Uganda, although the adjusted population attributable fraction is modest. The prevention of IPV should be a public health priority, and could contribute to HIV prevention.

Original languageEnglish (US)
Pages (from-to)1331-1338
Number of pages8
JournalAIDS
Volume27
Issue number8
DOIs
StatePublished - May 15 2013

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Uganda
HIV Infections
HIV
Population
Cohort Studies
Intimate Partner Violence
Health Priorities
Incidence
Condoms
Public Health

Keywords

  • Cohort studies
  • HIV
  • Uganda
  • Violence

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Kouyoumdjian, F. G., Calzavara, L. M., Bondy, S. J., O'Campo, P., Serwadda, D., Nalugoda, F., ... Gray, R. H. (2013). Intimate partner violence is associated with incident HIV infection in women in Uganda. AIDS, 27(8), 1331-1338. https://doi.org/10.1097/QAD.0b013e32835fd851

Intimate partner violence is associated with incident HIV infection in women in Uganda. / Kouyoumdjian, Fiona G.; Calzavara, Liviana M.; Bondy, Susan J.; O'Campo, Patricia; Serwadda, David; Nalugoda, Fred; Kagaayi, Joseph; Kigozi, Godfrey; Wawer, Maria J; Gray, Ronald H.

In: AIDS, Vol. 27, No. 8, 15.05.2013, p. 1331-1338.

Research output: Contribution to journalArticle

Kouyoumdjian, FG, Calzavara, LM, Bondy, SJ, O'Campo, P, Serwadda, D, Nalugoda, F, Kagaayi, J, Kigozi, G, Wawer, MJ & Gray, RH 2013, 'Intimate partner violence is associated with incident HIV infection in women in Uganda', AIDS, vol. 27, no. 8, pp. 1331-1338. https://doi.org/10.1097/QAD.0b013e32835fd851
Kouyoumdjian FG, Calzavara LM, Bondy SJ, O'Campo P, Serwadda D, Nalugoda F et al. Intimate partner violence is associated with incident HIV infection in women in Uganda. AIDS. 2013 May 15;27(8):1331-1338. https://doi.org/10.1097/QAD.0b013e32835fd851
Kouyoumdjian, Fiona G. ; Calzavara, Liviana M. ; Bondy, Susan J. ; O'Campo, Patricia ; Serwadda, David ; Nalugoda, Fred ; Kagaayi, Joseph ; Kigozi, Godfrey ; Wawer, Maria J ; Gray, Ronald H. / Intimate partner violence is associated with incident HIV infection in women in Uganda. In: AIDS. 2013 ; Vol. 27, No. 8. pp. 1331-1338.
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abstract = "Objectives: To quantify the association between intimate partner violence (IPV) and incident HIV infection in women in the Rakai Community Cohort Study between 2000 and 2009. Design and methods: Data were from the Rakai Community Cohort Study annual surveys between 2000 and 2009. Longitudinal data analysis was used to estimate the adjusted incidence rate ratio (IRR) of incident HIV associated with IPV in sexually active women aged 15-49 years, using a multivariable Poisson regression model with random effects. The population attributable fraction was calculated. Putative mediators were assessed using Baron and Kenny's criteria and the Sobel-Goodman test. Results: Women who had ever experienced IPV had an adjusted IRR of incident HIV infection of 1.55 (95{\%} CI1.25-1.94, P = 0.000), compared with women who had never experienced IPV. Risk of HIV infection tended to be greater for longer duration of IPV exposure and for women exposed to more severe and more frequent IPV. The adjusted population attributable fraction of incident HIV attributable to IPV was 22.2{\%} (95{\%} CI 12.5-30.4). There was no evidence that either condom use or number of sex partners in the past year mediated the relationship between IPV and HIV. Conclusion: IPV is associated with incident HIV infection in a population-based cohort in Uganda, although the adjusted population attributable fraction is modest. The prevention of IPV should be a public health priority, and could contribute to HIV prevention.",
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AU - Serwadda, David

AU - Nalugoda, Fred

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