Interventions to increase adherence to micronutrient supplementation during pregnancy: a protocol for a systematic review

Filomena Gomes, Gilles Bergeron, Megan W. Bourassa, Diana Dallmann, Jenna Golan, Kristen M. Hurley, Shannon E. King, Ana Carolina Feldenheimer da Silva, Saurabh Mehta

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Micronutrient supplementation during pregnancy has been shown to be a cost-effective method to reduce the risk of adverse pregnancy and birth outcomes. However, one of the main barriers to the successful implementation of a micronutrient supplementation program in pregnancy is poor adherence. Our review will assess the effectiveness of interventions designed to increase adherence to micronutrient supplements in pregnancy. Following the Cochrane Collaboration Methodology, we will start by conducting the literature searches on Medline (via PubMed), Embase, Scopus, Web of Science, and Cochrane Library, in addition to sources of gray literature, to retrieve all the available relevant studies. We will include randomized controlled trials and nonrandomized studies with a control group, where participants are pregnant women taking any micronutrient supplements in the context of antenatal care globally. We will include studies with targeted interventions designed to improve adherence to micronutrient supplementation in pregnant women compared with (1) usual care or no intervention or (2) other targeted micronutrient adherence intervention. Abstract selection, data extraction, and risk of bias assessment (according to the type of studies) will be conducted by two independent reviewers. The pooled results will be reported using the standardized mean differences for continuous data, and odds ratio or risk ratio for dichotomous data. We will assess sources of heterogeneity and publication bias. By following this protocol, we will systematically assess and synthesize the existing evidence about interventions designed to increase adherence to micronutrient supplementation in pregnant women. Understanding which strategies are more effective to increase the consumption of micronutrient supplements during this critical stage of life will have significant implications for clinicians and policymakers involved in the delivery of prenatal micronutrient supplementation interventions.

Original languageEnglish (US)
Pages (from-to)25-30
Number of pages6
JournalAnnals of the New York Academy of Sciences
Volume1470
Issue number1
DOIs
StatePublished - 2020

Keywords

  • adherence
  • compliance
  • micronutrients
  • pregnancy
  • supplementation

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • History and Philosophy of Science

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