Interventions Improve Poor Adherence with Once Daily Glaucoma Medications in Electronically Monitored Patients

Constance O. Okeke, Harry A Quigley, Henry D Jampel, Gui shuang Ying, Ryan J. Plyler, Yuzhen Jiang, David S Friedman

Research output: Contribution to journalArticle

Abstract

Purpose: To investigate the impact of an intervention program to improve adherence with topical, once daily therapy for glaucoma. Design: Randomized controlled clinical trial. Participants: Sixty-six patients with glaucoma being treated with a prostaglandin analog in 1 or both eyes at the Scheie Eye Institute or Wilmer Eye Institute between November 2006 and June 2007. Methods: In an observational study, participants who took 75% or fewer doses (as measured using the travoprost Dosing Aid [DA]) during an initial 3-month period were randomized into 2 groups. The intervention group watched an educational video, reviewed current barriers to drop-taking and possible solutions with a study coordinator, received regular phone call reminders, and had audible and visible reminders activated on their DA devices. The control group was told to take drops as prescribed and received no additional intervention. Main Outcome Measures: Change in drop use adherence as determined by the DA device. Results: In the 3-month observation period before randomization, intervention group patients had used a mean of 54±17% of scheduled doses, and this increased to 73±22% during the following 3-month period (P

Original languageEnglish (US)
Pages (from-to)2286-2293
Number of pages8
JournalOphthalmology
Volume116
Issue number12
DOIs
StatePublished - Dec 2009

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Glaucoma
Synthetic Prostaglandins
Equipment and Supplies
Random Allocation
Observational Studies
Randomized Controlled Trials
Observation
Outcome Assessment (Health Care)
Control Groups
Therapeutics
Travoprost

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Interventions Improve Poor Adherence with Once Daily Glaucoma Medications in Electronically Monitored Patients. / Okeke, Constance O.; Quigley, Harry A; Jampel, Henry D; Ying, Gui shuang; Plyler, Ryan J.; Jiang, Yuzhen; Friedman, David S.

In: Ophthalmology, Vol. 116, No. 12, 12.2009, p. 2286-2293.

Research output: Contribution to journalArticle

Okeke, Constance O. ; Quigley, Harry A ; Jampel, Henry D ; Ying, Gui shuang ; Plyler, Ryan J. ; Jiang, Yuzhen ; Friedman, David S. / Interventions Improve Poor Adherence with Once Daily Glaucoma Medications in Electronically Monitored Patients. In: Ophthalmology. 2009 ; Vol. 116, No. 12. pp. 2286-2293.
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