Interventions for seropositive injectors-research and evaluation: an integrated behavioral intervention with HIV-positive injection drug users to address medical care, adherence, and risk reduction.

David W. Purcell, Lisa R. Metsch, Mary Latka, Scott Santibanez, Cynthia A. Gómez, Lois Eldred, Carl A Latkin

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Behavioral interventions to address the complex medical and HIV risk reduction needs of HIV-seropositive (HIV-positive) injection drug users (IDUs) are urgently needed. We describe the development of Interventions for Seropositive Injectors-Research and Evaluation (INSPIRE), a randomized controlled trial of an integrated intervention for HIV-positive IDUs, and the characteristics of the baseline sample. METHODS: HIV-positive IDUs were recruited from community settings in 4 US cities. After completing a baseline assessment, participants who attended the first session were randomly assigned to (1) a 10-session peer mentoring intervention designed to improve utilization of HIV care, to improve adherence to HIV medications, and to reduce sexual and injection risk or (2) an 8-session videotape control. Periodic follow-up for 12 months is ongoing. RESULTS: A total of 1161 HIV-positive IDUs completed the baseline assessment, and 966 (83%) were randomized. Retention rates are greater than 80% for all follow-up periods. Approximately 79% of baseline participants reported a recent medical visit, 49% were taking highly active antiretroviral therapy, and 19% had an undetectable viral load. Use of injection and noninjection substances was prevalent, and sexual and injection risks were each reported by more than 25% of participants. CONCLUSION: There is a need for an integrated intervention for HIV-positive IDUs, and these data show the acceptability of such an approach.

Original languageEnglish (US)
JournalJournal of Acquired Immune Deficiency Syndromes
Volume37 Suppl 2
StatePublished - Oct 1 2004
Externally publishedYes

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Risk Reduction Behavior
Drug Users
HIV
Injections
Videotape Recording
Highly Active Antiretroviral Therapy
Viral Load
Randomized Controlled Trials

ASJC Scopus subject areas

  • Virology
  • Immunology

Cite this

@article{2fe455a25e8545629e489bee864c9708,
title = "Interventions for seropositive injectors-research and evaluation: an integrated behavioral intervention with HIV-positive injection drug users to address medical care, adherence, and risk reduction.",
abstract = "BACKGROUND: Behavioral interventions to address the complex medical and HIV risk reduction needs of HIV-seropositive (HIV-positive) injection drug users (IDUs) are urgently needed. We describe the development of Interventions for Seropositive Injectors-Research and Evaluation (INSPIRE), a randomized controlled trial of an integrated intervention for HIV-positive IDUs, and the characteristics of the baseline sample. METHODS: HIV-positive IDUs were recruited from community settings in 4 US cities. After completing a baseline assessment, participants who attended the first session were randomly assigned to (1) a 10-session peer mentoring intervention designed to improve utilization of HIV care, to improve adherence to HIV medications, and to reduce sexual and injection risk or (2) an 8-session videotape control. Periodic follow-up for 12 months is ongoing. RESULTS: A total of 1161 HIV-positive IDUs completed the baseline assessment, and 966 (83{\%}) were randomized. Retention rates are greater than 80{\%} for all follow-up periods. Approximately 79{\%} of baseline participants reported a recent medical visit, 49{\%} were taking highly active antiretroviral therapy, and 19{\%} had an undetectable viral load. Use of injection and noninjection substances was prevalent, and sexual and injection risks were each reported by more than 25{\%} of participants. CONCLUSION: There is a need for an integrated intervention for HIV-positive IDUs, and these data show the acceptability of such an approach.",
author = "Purcell, {David W.} and Metsch, {Lisa R.} and Mary Latka and Scott Santibanez and G{\'o}mez, {Cynthia A.} and Lois Eldred and Latkin, {Carl A}",
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AU - Latka, Mary

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AU - Gómez, Cynthia A.

AU - Eldred, Lois

AU - Latkin, Carl A

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