TY - JOUR
T1 - Interstitial lung disease associated with the idiopathic inflammatory myopathies
T2 - What progress has been made in the past 35 years?
AU - Connors, Geoffrey R.
AU - Christopher-Stine, Lisa
AU - Oddis, Chester V.
AU - Danoff, Sonye K.
N1 - Funding Information:
Funding/Support: This work was supported by funding from the Lisa Sandler Spaeth Fund to S. K. D.
PY - 2010/12/1
Y1 - 2010/12/1
N2 - Interstitial lung disease is commonly associated with the autoimmune inflammatory myopathies dermatomyositis and polymyositis and accounts for significant morbidity and mortality in these conditions. In the 35 years since the association between inflammatory myopathy and interstitial lung disease was initially described, there has been progress in diagnosing and treating this disorder. Nevertheless, there remains much about pathogenesis and therapeutics to be learned. This review examines the changes in the understanding of this complex condition, highlighting recent advances and areas deserving of further study.
AB - Interstitial lung disease is commonly associated with the autoimmune inflammatory myopathies dermatomyositis and polymyositis and accounts for significant morbidity and mortality in these conditions. In the 35 years since the association between inflammatory myopathy and interstitial lung disease was initially described, there has been progress in diagnosing and treating this disorder. Nevertheless, there remains much about pathogenesis and therapeutics to be learned. This review examines the changes in the understanding of this complex condition, highlighting recent advances and areas deserving of further study.
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U2 - 10.1378/chest.10-0180
DO - 10.1378/chest.10-0180
M3 - Review article
C2 - 21138882
AN - SCOPUS:78649951827
SN - 0012-3692
VL - 138
SP - 1464
EP - 1474
JO - CHEST
JF - CHEST
IS - 6
ER -