Abstract
Electroporation of artificial lipid membranes was studied by applying a 10μs, 300-600mV rectangular voltage clamp pulse followed by a ramp of negative slope which decayed to zero in the subsequent 500μs. After the electroporating pulse the membrane conductance begins to increase after a variable time delay (latency time) and shows two distinct phases, a first phase in which conductance increases very rapidly followed by a second slow phase. The inter-relationships between breakdown voltage, latency time and the membrane conductance were investigated in 25 different bilayers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1177-1178 |
| Number of pages | 2 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 16 |
| Issue number | pt 2 |
| State | Published - Dec 1 1994 |
| Event | Proceedings of the 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 1 (of 2) - Baltimore, MD, USA Duration: Nov 3 1994 → Nov 6 1994 |
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics
Cite this
Sharma, V., Tung, L., & Murphy, J. C. (1994). Interrelationship among breakdown voltage, latency time and membrane conductance during electroporation of artificial lipid membranes. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 16(pt 2), 1177-1178.