Interrater reliability of the modified monitoring of side effects scale for assessment of adverse effects of psychiatric medication in clinical and research settings

Katie L. Nugent, Erin Spahr, Jaimie Toroney, Ramin Mojtabai, Carrie Nettles, Lydia W. Turner, Ashley Fenton, Amethyst Spivak, Bernadette A. Cullen, Anita Everett, William W. Eaton

Research output: Contribution to journalArticlepeer-review

Abstract

The assessment of adverse effects of psychiatric medications is important in clinical and research settings because they are often associated with medication discontinuation, symptom exacerbation, and reduced quality of life. Currently available assessment tools are either limited with regard to the number and variety of included adverse effects or are not practical for use in most clinical or research settings owing to specialized rater training required and administration length. This report describes a modification of the Monitoring of Side Effects Scale (MOSES), an established adverse effect rating scale, by adding severity anchors to improve its reliability and ease of use. Interrater reliability was good for 7 of the 8 bodily adverse effects assessed, with intraclass correlation coefficients ranging from 0.76 to 0.91 in a sample of patients with severe mental illness. This modified version of the Monitoring of Side Effects Scale holds promise as a useful tool for assessing medication adverse effects in clinical and research settings.

Original languageEnglish (US)
Pages (from-to)324-328
Number of pages5
JournalJournal of clinical psychopharmacology
Volume35
Issue number3
DOIs
StatePublished - Jun 13 2015

Keywords

  • Adverse effects
  • psychiatric medications
  • rating scales

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

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