International standards for newborn weight, length, and head circumference by gestational age and sex: The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project

Jos̈ Villar, Leila Cheikh Ismail, Cesar G. Victora, Eric O. Ohuma, Enrico Bertino, Doug G. Altman, Ann Lambert, Aris T. Papageorghiou, Maria Carvalho, Yasmin A. Jaffer, Michael G. Gravett, Manorama Purwar, Ihunnaya O. Frederick, Alison J. Noble, Ruyan Pang, Fernando C. Barros, Cameron Chumlea, Zulfiqar A. Bhutta, Stephen H. Kennedy, M. KatzM. K. Bhan, C. Garza, S. Zaidi, A. Langer, P. M. Rothwell, D. Weatherall, Z. A. Bhutta, J. Villar, S. Kennedy, D. G. Altman, F. C. Barros, E. Bertino, F. Burton, M. Carvalho, L. Cheikh Ismail, W. C. Chumlea, M. G. Gravett, Y. A Jaff Er, A. Lambert, P. Lumbiganon, J. A. Noble, R. Y. Pang, A. T. Papageorghiou, M. Purwar, J. Rivera, C. G. Victora, J. Villar, D. G. Altman, Z. A. Bhutta, S. Kennedy, A. Lambert, J. A. Noble, A. T. Papageorghiou, J. Villar, S. Kennedy, A. Lambert, A. T. Papageorghiou, M. Shorten, L. Hoch, H. E. Knight, E. O. Ohuma, C. Cosgrove, I. Blakey, D. G. Altman, E. O. Ohuma, J. Villar, D. G. Altman, F. Roseman, N. Kunnawar, S. H. Gu, J. H. Wang, M. H. Wu, M. Domingues, P. Gilli, L. Juodvirsiene, L. Hoch, N. Musee, H. Al-Jabri, S. Waller, C. Cosgrove, D. Muninzwa, E. O. Ohuma, D. Yellappan, A. Carter, D. Reade, R. Miller, A. T. Papageorghiou, L. Salomon, A. Leston, A. Mitidieri, F. Al-Aamri, W. Paulsene, J. Sande, W. K S Al-Zadjali, C. Batiuk, S. Bornemeier, M. Carvalho, M. Dighe, P. Gaglioti, N. Jacinta, S. Jaiswal, J. A. Noble, K. Oas, M. Oberto, E. Olearo, M. G. Owende, J. Shah, S. Sohoni, T. Todros, M. Venkataraman, S. Vinayak, L. Wang, D. Wilson, Q. Q. Wu, S. Zaidi, Y. Zhang, P. Chamberlain, D. Danelon, I. Sarris, J. Dhami, C. Ioannou, C. L. Knight, R. Napolitano, S. Wanyonyi, C. Pace, V. Mkrtychyan, L. Cheikh Ismail, W. C. Chumlea, F. Al-Habsi, Z. A. Bhutta, A. Carter, M. Alija, J. M. Jimenez-Bustos, J. Kizidio, F. Puglia, N. Kunnawar, H. Liu, S. Lloyd, D. Mota, R. Ochieng, C. Rossi, M. Sanchez Luna, Y. J. Shen, H. E. Knight, D. A. Rocco, I. O. Frederick, Z. A. Bhutta, E. Albernaz, M. Batra, B. A. Bhat, E. Bertino, P. Di Nicola, F. Giuliani, I. Rovelli, K. McCormick, R. Ochieng, R. Y. Pang, V. Paul, V. Rajan, A. Wilkinson, A. Varalda, B. Eskenazi, L. A. Corra, H. Dolk, J. Golding, A. Matijasevich, T. De Wet, J. J. Zhang, A. Bradman, D. Finkton, O. Burnham, F. Farhi, F. C. Barros, M. Domingues, S. Fonseca, A. Leston, A. Mitidieri, D. Mota, I. K. Sclowitz, M. Da Silveira, R. Y. Pang, Y. P. He, Y. Pan, Y. J. Shen, M. H. Wu, Q. Q. Wu, J. H. Wang, Y. Yuan, Y. Zhang, M. Purwar, A. Choudhary, S. Choudhary, S. Deshmukh, D. Dongaonkar, M. Ketkar, V. Khedikar, N. Kunnawar, C. Mahorkar, I. Mulik, K. Saboo, C. Shembekar, A. Singh, V. Taori, K. Tayade, A. Somani, E. Bertino, P. Di Nicola, M. Frigerio, G. Gilli, P. Gilli, M. Giolito, F. Giuliani, M. Oberto, L. Occhi, C. Rossi, I. Rovelli, F. Signorile, T. Stones, W. Todros, M. Carvalho, J. Kizidio, R. Ochieng, J. Shah, S. Vinayak, N. Musee, C. Kisiang'ani, D. Muninzwa, Y. A. Jaffer, J. Al-Abri, J. Al-Abduwani, F. M. Al-Habsi, H. Al-Lawatiya, B. Al-Rashidiya, W. K S Al-Zadjali, F. R. Juangco, M. Venkataraman, H. Al-Jabri, D. Yellappan, S. Kennedy, A. T. Papageorghiou, F. Roseman, A. Lambert, E. O. Ohuma, S. Lloyd, R. Napolitano, C. Ioannou, I. Sarris, M. G. Gravett, C. Batiuk, M. Batra, S. Bornemeier, M. Dighe, K. Oas, W. Paulsene, D. Wilson, I. O. Frederick, H. F. Andersen, S. E. Abbott, A. A. Carter, H. Algren, D. A. Rocco, T. K. Sorensen, D. Enquobahrie, S. Waller

Research output: Contribution to journalArticle

Abstract

Background In 2006, WHO published international growth standards for children younger than 5 years, which are now accepted worldwide. In the INTERGROWTH-21st Project, our aim was to complement them by developing international standards for fetuses, newborn infants, and the postnatal growth period of preterm infants. Methods INTERGROWTH-21st is a population-based project that assessed fetal growth and newborn size in eight geographically defi ned urban populations. These groups were selected because most of the health and nutrition needs of mothers were met, adequate antenatal care was provided, and there were no major environmental constraints on growth. As part of the Newborn Cross-Sectional Study (NCSS), a component of INTERGROWTH-21st Project, we measured weight, length, and head circumference in all newborn infants, in addition to collecting data prospectively for pregnancy and the perinatal period. To construct the newborn standards, we selected all pregnancies in women meeting (in addition to the underlying population characteristics) strict individual eligibility criteria for a population at low risk of impaired fetal growth (labelled the NCSS prescriptive subpopulation). Women had a reliable ultrasound estimate of gestational age using crown-rump length before 14 weeks of gestation or biparietal diameter if antenatal care started between 14 weeks and 24 weeks or less of gestation. Newborn anthropometric measures were obtained within 12 h of birth by identically trained anthropometric teams using the same equipment at all sites. Fractional polynomials assuming a skewed t distribution were used to estimate the fi tted centiles. Findings We identifi ed 20 486 (35%) eligible women from the 59 137 pregnant women enrolled in NCSS between May 14, 2009, and Aug 2, 2013. We calculated sex-specifi c observed and smoothed centiles for weight, length, and head circumference for gestational age at birth. The observed and smoothed centiles were almost identical. We present the 3rd, 10th, 50th, 90th, and 97th centile curves according to gestational age and sex. Interpretation We have developed, for routine clinical practice, international anthropometric standards to assess newborn size that are intended to complement the WHO Child Growth Standards and allow comparisons across multiethnic populations. Funding Bill & Melinda Gates Foundation.

Original languageEnglish (US)
Pages (from-to)857-868
Number of pages12
JournalThe Lancet
Volume384
Issue number9946
StatePublished - 2014
Externally publishedYes

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Gestational Age
Cross-Sectional Studies
Head
Newborn Infant
Weights and Measures
Pregnancy
Prenatal Care
Growth
Fetal Development
Parturition
Crown-Rump Length
Urban Population
Population Characteristics
Premature Infants
Population
Pregnant Women
Fetus
Mothers
Equipment and Supplies
Health

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Villar, J., Ismail, L. C., Victora, C. G., Ohuma, E. O., Bertino, E., Altman, D. G., ... Waller, S. (2014). International standards for newborn weight, length, and head circumference by gestational age and sex: The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project. The Lancet, 384(9946), 857-868.

International standards for newborn weight, length, and head circumference by gestational age and sex : The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project. / Villar, Jos̈; Ismail, Leila Cheikh; Victora, Cesar G.; Ohuma, Eric O.; Bertino, Enrico; Altman, Doug G.; Lambert, Ann; Papageorghiou, Aris T.; Carvalho, Maria; Jaffer, Yasmin A.; Gravett, Michael G.; Purwar, Manorama; Frederick, Ihunnaya O.; Noble, Alison J.; Pang, Ruyan; Barros, Fernando C.; Chumlea, Cameron; Bhutta, Zulfiqar A.; Kennedy, Stephen H.; Katz, M.; Bhan, M. K.; Garza, C.; Zaidi, S.; Langer, A.; Rothwell, P. M.; Weatherall, D.; Bhutta, Z. A.; Villar, J.; Kennedy, S.; Altman, D. G.; Barros, F. C.; Bertino, E.; Burton, F.; Carvalho, M.; Ismail, L. Cheikh; Chumlea, W. C.; Gravett, M. G.; Er, Y. A Jaff; Lambert, A.; Lumbiganon, P.; Noble, J. A.; Pang, R. Y.; Papageorghiou, A. T.; Purwar, M.; Rivera, J.; Victora, C. G.; Villar, J.; Altman, D. G.; Bhutta, Z. A.; Kennedy, S.; Lambert, A.; Noble, J. A.; Papageorghiou, A. T.; Villar, J.; Kennedy, S.; Lambert, A.; Papageorghiou, A. T.; Shorten, M.; Hoch, L.; Knight, H. E.; Ohuma, E. O.; Cosgrove, C.; Blakey, I.; Altman, D. G.; Ohuma, E. O.; Villar, J.; Altman, D. G.; Roseman, F.; Kunnawar, N.; Gu, S. H.; Wang, J. H.; Wu, M. H.; Domingues, M.; Gilli, P.; Juodvirsiene, L.; Hoch, L.; Musee, N.; Al-Jabri, H.; Waller, S.; Cosgrove, C.; Muninzwa, D.; Ohuma, E. O.; Yellappan, D.; Carter, A.; Reade, D.; Miller, R.; Papageorghiou, A. T.; Salomon, L.; Leston, A.; Mitidieri, A.; Al-Aamri, F.; Paulsene, W.; Sande, J.; Al-Zadjali, W. K S; Batiuk, C.; Bornemeier, S.; Carvalho, M.; Dighe, M.; Gaglioti, P.; Jacinta, N.; Jaiswal, S.; Noble, J. A.; Oas, K.; Oberto, M.; Olearo, E.; Owende, M. G.; Shah, J.; Sohoni, S.; Todros, T.; Venkataraman, M.; Vinayak, S.; Wang, L.; Wilson, D.; Wu, Q. Q.; Zaidi, S.; Zhang, Y.; Chamberlain, P.; Danelon, D.; Sarris, I.; Dhami, J.; Ioannou, C.; Knight, C. L.; Napolitano, R.; Wanyonyi, S.; Pace, C.; Mkrtychyan, V.; Ismail, L. Cheikh; Chumlea, W. C.; Al-Habsi, F.; Bhutta, Z. A.; Carter, A.; Alija, M.; Jimenez-Bustos, J. M.; Kizidio, J.; Puglia, F.; Kunnawar, N.; Liu, H.; Lloyd, S.; Mota, D.; Ochieng, R.; Rossi, C.; Luna, M. Sanchez; Shen, Y. J.; Knight, H. E.; Rocco, D. A.; Frederick, I. O.; Bhutta, Z. A.; Albernaz, E.; Batra, M.; Bhat, B. A.; Bertino, E.; Di Nicola, P.; Giuliani, F.; Rovelli, I.; McCormick, K.; Ochieng, R.; Pang, R. Y.; Paul, V.; Rajan, V.; Wilkinson, A.; Varalda, A.; Eskenazi, B.; Corra, L. A.; Dolk, H.; Golding, J.; Matijasevich, A.; De Wet, T.; Zhang, J. J.; Bradman, A.; Finkton, D.; Burnham, O.; Farhi, F.; Barros, F. C.; Domingues, M.; Fonseca, S.; Leston, A.; Mitidieri, A.; Mota, D.; Sclowitz, I. K.; Da Silveira, M.; Pang, R. Y.; He, Y. P.; Pan, Y.; Shen, Y. J.; Wu, M. H.; Wu, Q. Q.; Wang, J. H.; Yuan, Y.; Zhang, Y.; Purwar, M.; Choudhary, A.; Choudhary, S.; Deshmukh, S.; Dongaonkar, D.; Ketkar, M.; Khedikar, V.; Kunnawar, N.; Mahorkar, C.; Mulik, I.; Saboo, K.; Shembekar, C.; Singh, A.; Taori, V.; Tayade, K.; Somani, A.; Bertino, E.; Di Nicola, P.; Frigerio, M.; Gilli, G.; Gilli, P.; Giolito, M.; Giuliani, F.; Oberto, M.; Occhi, L.; Rossi, C.; Rovelli, I.; Signorile, F.; Stones, T.; Todros, W.; Carvalho, M.; Kizidio, J.; Ochieng, R.; Shah, J.; Vinayak, S.; Musee, N.; Kisiang'ani, C.; Muninzwa, D.; Jaffer, Y. A.; Al-Abri, J.; Al-Abduwani, J.; Al-Habsi, F. M.; Al-Lawatiya, H.; Al-Rashidiya, B.; Al-Zadjali, W. K S; Juangco, F. R.; Venkataraman, M.; Al-Jabri, H.; Yellappan, D.; Kennedy, S.; Papageorghiou, A. T.; Roseman, F.; Lambert, A.; Ohuma, E. O.; Lloyd, S.; Napolitano, R.; Ioannou, C.; Sarris, I.; Gravett, M. G.; Batiuk, C.; Batra, M.; Bornemeier, S.; Dighe, M.; Oas, K.; Paulsene, W.; Wilson, D.; Frederick, I. O.; Andersen, H. F.; Abbott, S. E.; Carter, A. A.; Algren, H.; Rocco, D. A.; Sorensen, T. K.; Enquobahrie, D.; Waller, S.

In: The Lancet, Vol. 384, No. 9946, 2014, p. 857-868.

Research output: Contribution to journalArticle

Villar, J, Ismail, LC, Victora, CG, Ohuma, EO, Bertino, E, Altman, DG, Lambert, A, Papageorghiou, AT, Carvalho, M, Jaffer, YA, Gravett, MG, Purwar, M, Frederick, IO, Noble, AJ, Pang, R, Barros, FC, Chumlea, C, Bhutta, ZA, Kennedy, SH, Katz, M, Bhan, MK, Garza, C, Zaidi, S, Langer, A, Rothwell, PM, Weatherall, D, Bhutta, ZA, Villar, J, Kennedy, S, Altman, DG, Barros, FC, Bertino, E, Burton, F, Carvalho, M, Ismail, LC, Chumlea, WC, Gravett, MG, Er, YAJ, Lambert, A, Lumbiganon, P, Noble, JA, Pang, RY, Papageorghiou, AT, Purwar, M, Rivera, J, Victora, CG, Villar, J, Altman, DG, Bhutta, ZA, Kennedy, S, Lambert, A, Noble, JA, Papageorghiou, AT, Villar, J, Kennedy, S, Lambert, A, Papageorghiou, AT, Shorten, M, Hoch, L, Knight, HE, Ohuma, EO, Cosgrove, C, Blakey, I, Altman, DG, Ohuma, EO, Villar, J, Altman, DG, Roseman, F, Kunnawar, N, Gu, SH, Wang, JH, Wu, MH, Domingues, M, Gilli, P, Juodvirsiene, L, Hoch, L, Musee, N, Al-Jabri, H, Waller, S, Cosgrove, C, Muninzwa, D, Ohuma, EO, Yellappan, D, Carter, A, Reade, D, Miller, R, Papageorghiou, AT, Salomon, L, Leston, A, Mitidieri, A, Al-Aamri, F, Paulsene, W, Sande, J, Al-Zadjali, WKS, Batiuk, C, Bornemeier, S, Carvalho, M, Dighe, M, Gaglioti, P, Jacinta, N, Jaiswal, S, Noble, JA, Oas, K, Oberto, M, Olearo, E, Owende, MG, Shah, J, Sohoni, S, Todros, T, Venkataraman, M, Vinayak, S, Wang, L, Wilson, D, Wu, QQ, Zaidi, S, Zhang, Y, Chamberlain, P, Danelon, D, Sarris, I, Dhami, J, Ioannou, C, Knight, CL, Napolitano, R, Wanyonyi, S, Pace, C, Mkrtychyan, V, Ismail, LC, Chumlea, WC, Al-Habsi, F, Bhutta, ZA, Carter, A, Alija, M, Jimenez-Bustos, JM, Kizidio, J, Puglia, F, Kunnawar, N, Liu, H, Lloyd, S, Mota, D, Ochieng, R, Rossi, C, Luna, MS, Shen, YJ, Knight, HE, Rocco, DA, Frederick, IO, Bhutta, ZA, Albernaz, E, Batra, M, Bhat, BA, Bertino, E, Di Nicola, P, Giuliani, F, Rovelli, I, McCormick, K, Ochieng, R, Pang, RY, Paul, V, Rajan, V, Wilkinson, A, Varalda, A, Eskenazi, B, Corra, LA, Dolk, H, Golding, J, Matijasevich, A, De Wet, T, Zhang, JJ, Bradman, A, Finkton, D, Burnham, O, Farhi, F, Barros, FC, Domingues, M, Fonseca, S, Leston, A, Mitidieri, A, Mota, D, Sclowitz, IK, Da Silveira, M, Pang, RY, He, YP, Pan, Y, Shen, YJ, Wu, MH, Wu, QQ, Wang, JH, Yuan, Y, Zhang, Y, Purwar, M, Choudhary, A, Choudhary, S, Deshmukh, S, Dongaonkar, D, Ketkar, M, Khedikar, V, Kunnawar, N, Mahorkar, C, Mulik, I, Saboo, K, Shembekar, C, Singh, A, Taori, V, Tayade, K, Somani, A, Bertino, E, Di Nicola, P, Frigerio, M, Gilli, G, Gilli, P, Giolito, M, Giuliani, F, Oberto, M, Occhi, L, Rossi, C, Rovelli, I, Signorile, F, Stones, T, Todros, W, Carvalho, M, Kizidio, J, Ochieng, R, Shah, J, Vinayak, S, Musee, N, Kisiang'ani, C, Muninzwa, D, Jaffer, YA, Al-Abri, J, Al-Abduwani, J, Al-Habsi, FM, Al-Lawatiya, H, Al-Rashidiya, B, Al-Zadjali, WKS, Juangco, FR, Venkataraman, M, Al-Jabri, H, Yellappan, D, Kennedy, S, Papageorghiou, AT, Roseman, F, Lambert, A, Ohuma, EO, Lloyd, S, Napolitano, R, Ioannou, C, Sarris, I, Gravett, MG, Batiuk, C, Batra, M, Bornemeier, S, Dighe, M, Oas, K, Paulsene, W, Wilson, D, Frederick, IO, Andersen, HF, Abbott, SE, Carter, AA, Algren, H, Rocco, DA, Sorensen, TK, Enquobahrie, D & Waller, S 2014, 'International standards for newborn weight, length, and head circumference by gestational age and sex: The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project', The Lancet, vol. 384, no. 9946, pp. 857-868.
Villar, Jos̈ ; Ismail, Leila Cheikh ; Victora, Cesar G. ; Ohuma, Eric O. ; Bertino, Enrico ; Altman, Doug G. ; Lambert, Ann ; Papageorghiou, Aris T. ; Carvalho, Maria ; Jaffer, Yasmin A. ; Gravett, Michael G. ; Purwar, Manorama ; Frederick, Ihunnaya O. ; Noble, Alison J. ; Pang, Ruyan ; Barros, Fernando C. ; Chumlea, Cameron ; Bhutta, Zulfiqar A. ; Kennedy, Stephen H. ; Katz, M. ; Bhan, M. K. ; Garza, C. ; Zaidi, S. ; Langer, A. ; Rothwell, P. M. ; Weatherall, D. ; Bhutta, Z. A. ; Villar, J. ; Kennedy, S. ; Altman, D. G. ; Barros, F. C. ; Bertino, E. ; Burton, F. ; Carvalho, M. ; Ismail, L. Cheikh ; Chumlea, W. C. ; Gravett, M. G. ; Er, Y. A Jaff ; Lambert, A. ; Lumbiganon, P. ; Noble, J. A. ; Pang, R. Y. ; Papageorghiou, A. T. ; Purwar, M. ; Rivera, J. ; Victora, C. G. ; Villar, J. ; Altman, D. G. ; Bhutta, Z. A. ; Kennedy, S. ; Lambert, A. ; Noble, J. A. ; Papageorghiou, A. T. ; Villar, J. ; Kennedy, S. ; Lambert, A. ; Papageorghiou, A. T. ; Shorten, M. ; Hoch, L. ; Knight, H. E. ; Ohuma, E. O. ; Cosgrove, C. ; Blakey, I. ; Altman, D. G. ; Ohuma, E. O. ; Villar, J. ; Altman, D. G. ; Roseman, F. ; Kunnawar, N. ; Gu, S. H. ; Wang, J. H. ; Wu, M. H. ; Domingues, M. ; Gilli, P. ; Juodvirsiene, L. ; Hoch, L. ; Musee, N. ; Al-Jabri, H. ; Waller, S. ; Cosgrove, C. ; Muninzwa, D. ; Ohuma, E. O. ; Yellappan, D. ; Carter, A. ; Reade, D. ; Miller, R. ; Papageorghiou, A. T. ; Salomon, L. ; Leston, A. ; Mitidieri, A. ; Al-Aamri, F. ; Paulsene, W. ; Sande, J. ; Al-Zadjali, W. K S ; Batiuk, C. ; Bornemeier, S. ; Carvalho, M. ; Dighe, M. ; Gaglioti, P. ; Jacinta, N. ; Jaiswal, S. ; Noble, J. A. ; Oas, K. ; Oberto, M. ; Olearo, E. ; Owende, M. G. ; Shah, J. ; Sohoni, S. ; Todros, T. ; Venkataraman, M. ; Vinayak, S. ; Wang, L. ; Wilson, D. ; Wu, Q. Q. ; Zaidi, S. ; Zhang, Y. ; Chamberlain, P. ; Danelon, D. ; Sarris, I. ; Dhami, J. ; Ioannou, C. ; Knight, C. L. ; Napolitano, R. ; Wanyonyi, S. ; Pace, C. ; Mkrtychyan, V. ; Ismail, L. Cheikh ; Chumlea, W. C. ; Al-Habsi, F. ; Bhutta, Z. A. ; Carter, A. ; Alija, M. ; Jimenez-Bustos, J. M. ; Kizidio, J. ; Puglia, F. ; Kunnawar, N. ; Liu, H. ; Lloyd, S. ; Mota, D. ; Ochieng, R. ; Rossi, C. ; Luna, M. Sanchez ; Shen, Y. J. ; Knight, H. E. ; Rocco, D. A. ; Frederick, I. O. ; Bhutta, Z. A. ; Albernaz, E. ; Batra, M. ; Bhat, B. A. ; Bertino, E. ; Di Nicola, P. ; Giuliani, F. ; Rovelli, I. ; McCormick, K. ; Ochieng, R. ; Pang, R. Y. ; Paul, V. ; Rajan, V. ; Wilkinson, A. ; Varalda, A. ; Eskenazi, B. ; Corra, L. A. ; Dolk, H. ; Golding, J. ; Matijasevich, A. ; De Wet, T. ; Zhang, J. J. ; Bradman, A. ; Finkton, D. ; Burnham, O. ; Farhi, F. ; Barros, F. C. ; Domingues, M. ; Fonseca, S. ; Leston, A. ; Mitidieri, A. ; Mota, D. ; Sclowitz, I. K. ; Da Silveira, M. ; Pang, R. Y. ; He, Y. P. ; Pan, Y. ; Shen, Y. J. ; Wu, M. H. ; Wu, Q. Q. ; Wang, J. H. ; Yuan, Y. ; Zhang, Y. ; Purwar, M. ; Choudhary, A. ; Choudhary, S. ; Deshmukh, S. ; Dongaonkar, D. ; Ketkar, M. ; Khedikar, V. ; Kunnawar, N. ; Mahorkar, C. ; Mulik, I. ; Saboo, K. ; Shembekar, C. ; Singh, A. ; Taori, V. ; Tayade, K. ; Somani, A. ; Bertino, E. ; Di Nicola, P. ; Frigerio, M. ; Gilli, G. ; Gilli, P. ; Giolito, M. ; Giuliani, F. ; Oberto, M. ; Occhi, L. ; Rossi, C. ; Rovelli, I. ; Signorile, F. ; Stones, T. ; Todros, W. ; Carvalho, M. ; Kizidio, J. ; Ochieng, R. ; Shah, J. ; Vinayak, S. ; Musee, N. ; Kisiang'ani, C. ; Muninzwa, D. ; Jaffer, Y. A. ; Al-Abri, J. ; Al-Abduwani, J. ; Al-Habsi, F. M. ; Al-Lawatiya, H. ; Al-Rashidiya, B. ; Al-Zadjali, W. K S ; Juangco, F. R. ; Venkataraman, M. ; Al-Jabri, H. ; Yellappan, D. ; Kennedy, S. ; Papageorghiou, A. T. ; Roseman, F. ; Lambert, A. ; Ohuma, E. O. ; Lloyd, S. ; Napolitano, R. ; Ioannou, C. ; Sarris, I. ; Gravett, M. G. ; Batiuk, C. ; Batra, M. ; Bornemeier, S. ; Dighe, M. ; Oas, K. ; Paulsene, W. ; Wilson, D. ; Frederick, I. O. ; Andersen, H. F. ; Abbott, S. E. ; Carter, A. A. ; Algren, H. ; Rocco, D. A. ; Sorensen, T. K. ; Enquobahrie, D. ; Waller, S. / International standards for newborn weight, length, and head circumference by gestational age and sex : The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project. In: The Lancet. 2014 ; Vol. 384, No. 9946. pp. 857-868.
@article{65867d1cea314bc1b9ca53b9fba433e1,
title = "International standards for newborn weight, length, and head circumference by gestational age and sex: The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project",
abstract = "Background In 2006, WHO published international growth standards for children younger than 5 years, which are now accepted worldwide. In the INTERGROWTH-21st Project, our aim was to complement them by developing international standards for fetuses, newborn infants, and the postnatal growth period of preterm infants. Methods INTERGROWTH-21st is a population-based project that assessed fetal growth and newborn size in eight geographically defi ned urban populations. These groups were selected because most of the health and nutrition needs of mothers were met, adequate antenatal care was provided, and there were no major environmental constraints on growth. As part of the Newborn Cross-Sectional Study (NCSS), a component of INTERGROWTH-21st Project, we measured weight, length, and head circumference in all newborn infants, in addition to collecting data prospectively for pregnancy and the perinatal period. To construct the newborn standards, we selected all pregnancies in women meeting (in addition to the underlying population characteristics) strict individual eligibility criteria for a population at low risk of impaired fetal growth (labelled the NCSS prescriptive subpopulation). Women had a reliable ultrasound estimate of gestational age using crown-rump length before 14 weeks of gestation or biparietal diameter if antenatal care started between 14 weeks and 24 weeks or less of gestation. Newborn anthropometric measures were obtained within 12 h of birth by identically trained anthropometric teams using the same equipment at all sites. Fractional polynomials assuming a skewed t distribution were used to estimate the fi tted centiles. Findings We identifi ed 20 486 (35{\%}) eligible women from the 59 137 pregnant women enrolled in NCSS between May 14, 2009, and Aug 2, 2013. We calculated sex-specifi c observed and smoothed centiles for weight, length, and head circumference for gestational age at birth. The observed and smoothed centiles were almost identical. We present the 3rd, 10th, 50th, 90th, and 97th centile curves according to gestational age and sex. Interpretation We have developed, for routine clinical practice, international anthropometric standards to assess newborn size that are intended to complement the WHO Child Growth Standards and allow comparisons across multiethnic populations. Funding Bill & Melinda Gates Foundation.",
author = "Jos̈ Villar and Ismail, {Leila Cheikh} and Victora, {Cesar G.} and Ohuma, {Eric O.} and Enrico Bertino and Altman, {Doug G.} and Ann Lambert and Papageorghiou, {Aris T.} and Maria Carvalho and Jaffer, {Yasmin A.} and Gravett, {Michael G.} and Manorama Purwar and Frederick, {Ihunnaya O.} and Noble, {Alison J.} and Ruyan Pang and Barros, {Fernando C.} and Cameron Chumlea and Bhutta, {Zulfiqar A.} and Kennedy, {Stephen H.} and M. Katz and Bhan, {M. K.} and C. Garza and S. Zaidi and A. Langer and Rothwell, {P. M.} and D. Weatherall and Bhutta, {Z. A.} and J. Villar and S. Kennedy and Altman, {D. G.} and Barros, {F. C.} and E. Bertino and F. Burton and M. Carvalho and Ismail, {L. Cheikh} and Chumlea, {W. C.} and Gravett, {M. G.} and Er, {Y. A Jaff} and A. Lambert and P. Lumbiganon and Noble, {J. A.} and Pang, {R. Y.} and Papageorghiou, {A. T.} and M. Purwar and J. Rivera and Victora, {C. G.} and J. Villar and Altman, {D. G.} and Bhutta, {Z. A.} and S. Kennedy and A. Lambert and Noble, {J. A.} and Papageorghiou, {A. T.} and J. Villar and S. Kennedy and A. Lambert and Papageorghiou, {A. T.} and M. Shorten and L. Hoch and Knight, {H. E.} and Ohuma, {E. O.} and C. Cosgrove and I. Blakey and Altman, {D. G.} and Ohuma, {E. O.} and J. Villar and Altman, {D. G.} and F. Roseman and N. Kunnawar and Gu, {S. H.} and Wang, {J. H.} and Wu, {M. H.} and M. Domingues and P. Gilli and L. Juodvirsiene and L. Hoch and N. Musee and H. Al-Jabri and S. Waller and C. Cosgrove and D. Muninzwa and Ohuma, {E. O.} and D. Yellappan and A. Carter and D. Reade and R. Miller and Papageorghiou, {A. T.} and L. Salomon and A. Leston and A. Mitidieri and F. Al-Aamri and W. Paulsene and J. Sande and Al-Zadjali, {W. K S} and C. Batiuk and S. Bornemeier and M. Carvalho and M. Dighe and P. Gaglioti and N. Jacinta and S. Jaiswal and Noble, {J. A.} and K. Oas and M. Oberto and E. Olearo and Owende, {M. G.} and J. Shah and S. Sohoni and T. Todros and M. Venkataraman and S. Vinayak and L. Wang and D. Wilson and Wu, {Q. Q.} and S. Zaidi and Y. Zhang and P. Chamberlain and D. Danelon and I. Sarris and J. Dhami and C. Ioannou and Knight, {C. L.} and R. Napolitano and S. Wanyonyi and C. Pace and V. Mkrtychyan and Ismail, {L. Cheikh} and Chumlea, {W. C.} and F. Al-Habsi and Bhutta, {Z. A.} and A. Carter and M. Alija and Jimenez-Bustos, {J. M.} and J. Kizidio and F. Puglia and N. Kunnawar and H. Liu and S. Lloyd and D. Mota and R. Ochieng and C. Rossi and Luna, {M. Sanchez} and Shen, {Y. J.} and Knight, {H. E.} and Rocco, {D. A.} and Frederick, {I. O.} and Bhutta, {Z. A.} and E. Albernaz and M. Batra and Bhat, {B. A.} and E. Bertino and {Di Nicola}, P. and F. Giuliani and I. Rovelli and K. McCormick and R. Ochieng and Pang, {R. Y.} and V. Paul and V. Rajan and A. Wilkinson and A. Varalda and B. Eskenazi and Corra, {L. A.} and H. Dolk and J. Golding and A. Matijasevich and {De Wet}, T. and Zhang, {J. J.} and A. Bradman and D. Finkton and O. Burnham and F. Farhi and Barros, {F. C.} and M. Domingues and S. Fonseca and A. Leston and A. Mitidieri and D. Mota and Sclowitz, {I. K.} and {Da Silveira}, M. and Pang, {R. Y.} and He, {Y. P.} and Y. Pan and Shen, {Y. J.} and Wu, {M. H.} and Wu, {Q. Q.} and Wang, {J. H.} and Y. Yuan and Y. Zhang and M. Purwar and A. Choudhary and S. Choudhary and S. Deshmukh and D. Dongaonkar and M. Ketkar and V. Khedikar and N. Kunnawar and C. Mahorkar and I. Mulik and K. Saboo and C. Shembekar and A. Singh and V. Taori and K. Tayade and A. Somani and E. Bertino and {Di Nicola}, P. and M. Frigerio and G. Gilli and P. Gilli and M. Giolito and F. Giuliani and M. Oberto and L. Occhi and C. Rossi and I. Rovelli and F. Signorile and T. Stones and W. Todros and M. Carvalho and J. Kizidio and R. Ochieng and J. Shah and S. Vinayak and N. Musee and C. Kisiang'ani and D. Muninzwa and Jaffer, {Y. A.} and J. Al-Abri and J. Al-Abduwani and Al-Habsi, {F. M.} and H. Al-Lawatiya and B. Al-Rashidiya and Al-Zadjali, {W. K S} and Juangco, {F. R.} and M. Venkataraman and H. Al-Jabri and D. Yellappan and S. Kennedy and Papageorghiou, {A. T.} and F. Roseman and A. Lambert and Ohuma, {E. O.} and S. Lloyd and R. Napolitano and C. Ioannou and I. Sarris and Gravett, {M. G.} and C. Batiuk and M. Batra and S. Bornemeier and M. Dighe and K. Oas and W. Paulsene and D. Wilson and Frederick, {I. O.} and Andersen, {H. F.} and Abbott, {S. E.} and Carter, {A. A.} and H. Algren and Rocco, {D. A.} and Sorensen, {T. K.} and D. Enquobahrie and S. Waller",
year = "2014",
language = "English (US)",
volume = "384",
pages = "857--868",
journal = "The Lancet",
issn = "0140-6736",
publisher = "Elsevier Limited",
number = "9946",

}

TY - JOUR

T1 - International standards for newborn weight, length, and head circumference by gestational age and sex

T2 - The Newborn Cross-Sectional Study of the INTERGROWTH-21st Project

AU - Villar, Jos̈

AU - Ismail, Leila Cheikh

AU - Victora, Cesar G.

AU - Ohuma, Eric O.

AU - Bertino, Enrico

AU - Altman, Doug G.

AU - Lambert, Ann

AU - Papageorghiou, Aris T.

AU - Carvalho, Maria

AU - Jaffer, Yasmin A.

AU - Gravett, Michael G.

AU - Purwar, Manorama

AU - Frederick, Ihunnaya O.

AU - Noble, Alison J.

AU - Pang, Ruyan

AU - Barros, Fernando C.

AU - Chumlea, Cameron

AU - Bhutta, Zulfiqar A.

AU - Kennedy, Stephen H.

AU - Katz, M.

AU - Bhan, M. K.

AU - Garza, C.

AU - Zaidi, S.

AU - Langer, A.

AU - Rothwell, P. M.

AU - Weatherall, D.

AU - Bhutta, Z. A.

AU - Villar, J.

AU - Kennedy, S.

AU - Altman, D. G.

AU - Barros, F. C.

AU - Bertino, E.

AU - Burton, F.

AU - Carvalho, M.

AU - Ismail, L. Cheikh

AU - Chumlea, W. C.

AU - Gravett, M. G.

AU - Er, Y. A Jaff

AU - Lambert, A.

AU - Lumbiganon, P.

AU - Noble, J. A.

AU - Pang, R. Y.

AU - Papageorghiou, A. T.

AU - Purwar, M.

AU - Rivera, J.

AU - Victora, C. G.

AU - Villar, J.

AU - Altman, D. G.

AU - Bhutta, Z. A.

AU - Kennedy, S.

AU - Lambert, A.

AU - Noble, J. A.

AU - Papageorghiou, A. T.

AU - Villar, J.

AU - Kennedy, S.

AU - Lambert, A.

AU - Papageorghiou, A. T.

AU - Shorten, M.

AU - Hoch, L.

AU - Knight, H. E.

AU - Ohuma, E. O.

AU - Cosgrove, C.

AU - Blakey, I.

AU - Altman, D. G.

AU - Ohuma, E. O.

AU - Villar, J.

AU - Altman, D. G.

AU - Roseman, F.

AU - Kunnawar, N.

AU - Gu, S. H.

AU - Wang, J. H.

AU - Wu, M. H.

AU - Domingues, M.

AU - Gilli, P.

AU - Juodvirsiene, L.

AU - Hoch, L.

AU - Musee, N.

AU - Al-Jabri, H.

AU - Waller, S.

AU - Cosgrove, C.

AU - Muninzwa, D.

AU - Ohuma, E. O.

AU - Yellappan, D.

AU - Carter, A.

AU - Reade, D.

AU - Miller, R.

AU - Papageorghiou, A. T.

AU - Salomon, L.

AU - Leston, A.

AU - Mitidieri, A.

AU - Al-Aamri, F.

AU - Paulsene, W.

AU - Sande, J.

AU - Al-Zadjali, W. K S

AU - Batiuk, C.

AU - Bornemeier, S.

AU - Carvalho, M.

AU - Dighe, M.

AU - Gaglioti, P.

AU - Jacinta, N.

AU - Jaiswal, S.

AU - Noble, J. A.

AU - Oas, K.

AU - Oberto, M.

AU - Olearo, E.

AU - Owende, M. G.

AU - Shah, J.

AU - Sohoni, S.

AU - Todros, T.

AU - Venkataraman, M.

AU - Vinayak, S.

AU - Wang, L.

AU - Wilson, D.

AU - Wu, Q. Q.

AU - Zaidi, S.

AU - Zhang, Y.

AU - Chamberlain, P.

AU - Danelon, D.

AU - Sarris, I.

AU - Dhami, J.

AU - Ioannou, C.

AU - Knight, C. L.

AU - Napolitano, R.

AU - Wanyonyi, S.

AU - Pace, C.

AU - Mkrtychyan, V.

AU - Ismail, L. Cheikh

AU - Chumlea, W. C.

AU - Al-Habsi, F.

AU - Bhutta, Z. A.

AU - Carter, A.

AU - Alija, M.

AU - Jimenez-Bustos, J. M.

AU - Kizidio, J.

AU - Puglia, F.

AU - Kunnawar, N.

AU - Liu, H.

AU - Lloyd, S.

AU - Mota, D.

AU - Ochieng, R.

AU - Rossi, C.

AU - Luna, M. Sanchez

AU - Shen, Y. J.

AU - Knight, H. E.

AU - Rocco, D. A.

AU - Frederick, I. O.

AU - Bhutta, Z. A.

AU - Albernaz, E.

AU - Batra, M.

AU - Bhat, B. A.

AU - Bertino, E.

AU - Di Nicola, P.

AU - Giuliani, F.

AU - Rovelli, I.

AU - McCormick, K.

AU - Ochieng, R.

AU - Pang, R. Y.

AU - Paul, V.

AU - Rajan, V.

AU - Wilkinson, A.

AU - Varalda, A.

AU - Eskenazi, B.

AU - Corra, L. A.

AU - Dolk, H.

AU - Golding, J.

AU - Matijasevich, A.

AU - De Wet, T.

AU - Zhang, J. J.

AU - Bradman, A.

AU - Finkton, D.

AU - Burnham, O.

AU - Farhi, F.

AU - Barros, F. C.

AU - Domingues, M.

AU - Fonseca, S.

AU - Leston, A.

AU - Mitidieri, A.

AU - Mota, D.

AU - Sclowitz, I. K.

AU - Da Silveira, M.

AU - Pang, R. Y.

AU - He, Y. P.

AU - Pan, Y.

AU - Shen, Y. J.

AU - Wu, M. H.

AU - Wu, Q. Q.

AU - Wang, J. H.

AU - Yuan, Y.

AU - Zhang, Y.

AU - Purwar, M.

AU - Choudhary, A.

AU - Choudhary, S.

AU - Deshmukh, S.

AU - Dongaonkar, D.

AU - Ketkar, M.

AU - Khedikar, V.

AU - Kunnawar, N.

AU - Mahorkar, C.

AU - Mulik, I.

AU - Saboo, K.

AU - Shembekar, C.

AU - Singh, A.

AU - Taori, V.

AU - Tayade, K.

AU - Somani, A.

AU - Bertino, E.

AU - Di Nicola, P.

AU - Frigerio, M.

AU - Gilli, G.

AU - Gilli, P.

AU - Giolito, M.

AU - Giuliani, F.

AU - Oberto, M.

AU - Occhi, L.

AU - Rossi, C.

AU - Rovelli, I.

AU - Signorile, F.

AU - Stones, T.

AU - Todros, W.

AU - Carvalho, M.

AU - Kizidio, J.

AU - Ochieng, R.

AU - Shah, J.

AU - Vinayak, S.

AU - Musee, N.

AU - Kisiang'ani, C.

AU - Muninzwa, D.

AU - Jaffer, Y. A.

AU - Al-Abri, J.

AU - Al-Abduwani, J.

AU - Al-Habsi, F. M.

AU - Al-Lawatiya, H.

AU - Al-Rashidiya, B.

AU - Al-Zadjali, W. K S

AU - Juangco, F. R.

AU - Venkataraman, M.

AU - Al-Jabri, H.

AU - Yellappan, D.

AU - Kennedy, S.

AU - Papageorghiou, A. T.

AU - Roseman, F.

AU - Lambert, A.

AU - Ohuma, E. O.

AU - Lloyd, S.

AU - Napolitano, R.

AU - Ioannou, C.

AU - Sarris, I.

AU - Gravett, M. G.

AU - Batiuk, C.

AU - Batra, M.

AU - Bornemeier, S.

AU - Dighe, M.

AU - Oas, K.

AU - Paulsene, W.

AU - Wilson, D.

AU - Frederick, I. O.

AU - Andersen, H. F.

AU - Abbott, S. E.

AU - Carter, A. A.

AU - Algren, H.

AU - Rocco, D. A.

AU - Sorensen, T. K.

AU - Enquobahrie, D.

AU - Waller, S.

PY - 2014

Y1 - 2014

N2 - Background In 2006, WHO published international growth standards for children younger than 5 years, which are now accepted worldwide. In the INTERGROWTH-21st Project, our aim was to complement them by developing international standards for fetuses, newborn infants, and the postnatal growth period of preterm infants. Methods INTERGROWTH-21st is a population-based project that assessed fetal growth and newborn size in eight geographically defi ned urban populations. These groups were selected because most of the health and nutrition needs of mothers were met, adequate antenatal care was provided, and there were no major environmental constraints on growth. As part of the Newborn Cross-Sectional Study (NCSS), a component of INTERGROWTH-21st Project, we measured weight, length, and head circumference in all newborn infants, in addition to collecting data prospectively for pregnancy and the perinatal period. To construct the newborn standards, we selected all pregnancies in women meeting (in addition to the underlying population characteristics) strict individual eligibility criteria for a population at low risk of impaired fetal growth (labelled the NCSS prescriptive subpopulation). Women had a reliable ultrasound estimate of gestational age using crown-rump length before 14 weeks of gestation or biparietal diameter if antenatal care started between 14 weeks and 24 weeks or less of gestation. Newborn anthropometric measures were obtained within 12 h of birth by identically trained anthropometric teams using the same equipment at all sites. Fractional polynomials assuming a skewed t distribution were used to estimate the fi tted centiles. Findings We identifi ed 20 486 (35%) eligible women from the 59 137 pregnant women enrolled in NCSS between May 14, 2009, and Aug 2, 2013. We calculated sex-specifi c observed and smoothed centiles for weight, length, and head circumference for gestational age at birth. The observed and smoothed centiles were almost identical. We present the 3rd, 10th, 50th, 90th, and 97th centile curves according to gestational age and sex. Interpretation We have developed, for routine clinical practice, international anthropometric standards to assess newborn size that are intended to complement the WHO Child Growth Standards and allow comparisons across multiethnic populations. Funding Bill & Melinda Gates Foundation.

AB - Background In 2006, WHO published international growth standards for children younger than 5 years, which are now accepted worldwide. In the INTERGROWTH-21st Project, our aim was to complement them by developing international standards for fetuses, newborn infants, and the postnatal growth period of preterm infants. Methods INTERGROWTH-21st is a population-based project that assessed fetal growth and newborn size in eight geographically defi ned urban populations. These groups were selected because most of the health and nutrition needs of mothers were met, adequate antenatal care was provided, and there were no major environmental constraints on growth. As part of the Newborn Cross-Sectional Study (NCSS), a component of INTERGROWTH-21st Project, we measured weight, length, and head circumference in all newborn infants, in addition to collecting data prospectively for pregnancy and the perinatal period. To construct the newborn standards, we selected all pregnancies in women meeting (in addition to the underlying population characteristics) strict individual eligibility criteria for a population at low risk of impaired fetal growth (labelled the NCSS prescriptive subpopulation). Women had a reliable ultrasound estimate of gestational age using crown-rump length before 14 weeks of gestation or biparietal diameter if antenatal care started between 14 weeks and 24 weeks or less of gestation. Newborn anthropometric measures were obtained within 12 h of birth by identically trained anthropometric teams using the same equipment at all sites. Fractional polynomials assuming a skewed t distribution were used to estimate the fi tted centiles. Findings We identifi ed 20 486 (35%) eligible women from the 59 137 pregnant women enrolled in NCSS between May 14, 2009, and Aug 2, 2013. We calculated sex-specifi c observed and smoothed centiles for weight, length, and head circumference for gestational age at birth. The observed and smoothed centiles were almost identical. We present the 3rd, 10th, 50th, 90th, and 97th centile curves according to gestational age and sex. Interpretation We have developed, for routine clinical practice, international anthropometric standards to assess newborn size that are intended to complement the WHO Child Growth Standards and allow comparisons across multiethnic populations. Funding Bill & Melinda Gates Foundation.

UR - http://www.scopus.com/inward/record.url?scp=84907424655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907424655&partnerID=8YFLogxK

M3 - Article

C2 - 25209487

AN - SCOPUS:84907424655

VL - 384

SP - 857

EP - 868

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 9946

ER -