International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines from the Special Techniques and Ancillary Studies Group

Kathleen R. Cho, Kumarasen Cooper, Sabrina Croce, Bojana Djordevic, Simon Herrington, Brooke Howitt, Pei Hui, Philip Ip, Martin Koebel, Sigurd Lax, Bradley J. Quade, Patricia Shaw, August Vidal, Anna Yemelyanova, Blaise Clarke, Lora Hedrick Ellenson, Teri A. Longacre, Ie Ming Shih, W. Glenn McCluggage, Anais MalpicaEsther Oliva, Vinita Parkash, Xavier Matias-Guiu

Research output: Contribution to journalArticle

Abstract

The aim of this article is to propose guidelines and recommendations in problematic areas in pathologic reporting of endometrial carcinoma (EC) regarding special techniques and ancillary studies. An organizing committee designed a comprehensive survey with different questions related to pathologic features, diagnosis, and prognosis of EC that was sent to all members of the International Society of Gynecological Pathologists. The special techniques/ancillary studies group received 4 different questions to be addressed. Five members of the group reviewed the literature and came up with recommendations and an accompanying text which were discussed and agreed upon by all members of the group. Twelve different recommendations are made. They address the value of immunohistochemistry, ploidy, and molecular analysis for assessing prognosis in EC, the value of steroid hormone receptor analysis to predict response to hormone therapy, and parameters regarding applying immunohistochemistry and molecular tests for assessing mismatch deficiency in EC.

Original languageEnglish (US)
Pages (from-to)S114-S122
JournalInternational Journal of Gynecological Pathology
Volume38
Issue number1
DOIs
StatePublished - Jan 1 2019

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Keywords

  • Endometrial carcinoma
  • Guidelines
  • ISGyP
  • Molecular pathology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

Cite this

Cho, K. R., Cooper, K., Croce, S., Djordevic, B., Herrington, S., Howitt, B., Hui, P., Ip, P., Koebel, M., Lax, S., Quade, B. J., Shaw, P., Vidal, A., Yemelyanova, A., Clarke, B., Hedrick Ellenson, L., Longacre, T. A., Shih, I. M., Glenn McCluggage, W., ... Matias-Guiu, X. (2019). International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines from the Special Techniques and Ancillary Studies Group. International Journal of Gynecological Pathology, 38(1), S114-S122. https://doi.org/10.1097/PGP.0000000000000496