Intermittent hepatic vein balloon occlusion during radiofrequency ablation in the liver

Deepak Sudheendra, Ziv Neeman, Anthony Kam, Julia Locklin, Steven K. Libutti, Bradford J. Wood

Research output: Contribution to journalArticle


The purpose of the study was to assess the feasibility of intermittent hepatic vein balloon occlusion during percutaneous radiofrequency (RF) ablation. Eight non-anticoagulated patients who had primary (n = 2) and metastatic (n = 6) liver tumors with a mean diameter of 4.2 cm (range 2.4-6.5 cm) were treated, resulting in a mean ablation diameter of 6.3 cm (range 4.3-9.3 cm). Six of 9 (67%) of the balloon-occluded hepatic veins were patent. No clinical sequelae of thrombosis were noted. Mean length of follow-up with CT and/or MRI was 12 months. Local tumor control was achieved in 5 of 8 patients. Intermittent hepatic vein balloon occlusion could potentially be a low-risk adjunctive maneuver for thermal ablation therapy in the treatment of large tumors and tumors adjacent to large vessels.

Original languageEnglish (US)
Pages (from-to)1088-1092
Number of pages5
JournalCardiovascular and interventional radiology
Issue number6
StatePublished - Dec 1 2006



  • Hyperthermia
  • Liver neoplasms
  • Oncology
  • Radiofrequency (RF) ablation
  • Vascular occlusion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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