Interleukin 1 production by peripheral blood mononuclear cells from leprosy patients

Susan Watson, Ward Bullock, Kenrad Nelson, Victoria Schauf, Robert Gelber, Robert Jacobson

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Quantitation of interleukin 1 production by adherent mononuclear cells from peripheral blood was performed in patients with tuberculoid and lepromatous forms of leprosy. Cells from patients with tuberculoid leprosy either secreted interleukin 1 spontaneously or produced amounts within the normal range in response to lipopolysaccharide stimulation. Conversely, stimulated cells from lepromatous patients failed to produce interleukin 1 in 5 of 13 (38.5%) cases.

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalInfection and immunity
Volume45
Issue number3
DOIs
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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