Interleaved acquisition of lipid and water images of the heart using a double-inversion fast spin-echo method

Maria I. Altbach; Zhiqiang Li; Ali Bilgin; Frank I. Marcus; Vincent Sorrell; Arthur F. Gmitro; David A. Bluemke

doi:10.1002/mrm.20691

Interleaved acquisition of lipid and water images of the heart using a double-inversion fast spin-echo method

Maria I. Altbach, Zhiqiang Li, Ali Bilgin, Frank I. Marcus, Vincent Sorrell, Arthur F. Gmitro, David A. Bluemke

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

In this work we present a new method for the improved detection of lipid infiltration in the heart. The method employs a double-inversion fast spin-echo technique where the acquisition of water- and lipid-suppressed k-space data is alternated between TR periods to produce coregistered lipid and water images from data acquired in a breath hold. The lipid and water images can then be combined to generate a lipid/water image with reduced artifacts due to flow and excellent contrast between lipid and myocardium. The method is demonstrated in ex vivo tissue and in vivo. This novel method may improve the detection of lipid infiltration in the heart in pathologies such as arrhythmogenic right ventricular dysplasia.

Original language	English (US)
Pages (from-to)	1562-1568
Number of pages	7
Journal	Magnetic resonance in medicine
Volume	54
Issue number	6
DOIs	https://doi.org/10.1002/mrm.20691
State	Published - Dec 2005
Externally published	Yes

Keywords

ARVD
Cardiac
Fast spin echo
Lipid
MRI

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/mrm.20691

Cite this

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title = "Interleaved acquisition of lipid and water images of the heart using a double-inversion fast spin-echo method",

abstract = "In this work we present a new method for the improved detection of lipid infiltration in the heart. The method employs a double-inversion fast spin-echo technique where the acquisition of water- and lipid-suppressed k-space data is alternated between TR periods to produce coregistered lipid and water images from data acquired in a breath hold. The lipid and water images can then be combined to generate a lipid/water image with reduced artifacts due to flow and excellent contrast between lipid and myocardium. The method is demonstrated in ex vivo tissue and in vivo. This novel method may improve the detection of lipid infiltration in the heart in pathologies such as arrhythmogenic right ventricular dysplasia.",

keywords = "ARVD, Cardiac, Fast spin echo, Lipid, MRI",

author = "Altbach, {Maria I.} and Zhiqiang Li and Ali Bilgin and Marcus, {Frank I.} and Vincent Sorrell and Gmitro, {Arthur F.} and Bluemke, {David A.}",

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AU - Altbach, Maria I.

AU - Li, Zhiqiang

AU - Bilgin, Ali

AU - Marcus, Frank I.

AU - Sorrell, Vincent

AU - Gmitro, Arthur F.

AU - Bluemke, David A.

PY - 2005/12

Y1 - 2005/12

N2 - In this work we present a new method for the improved detection of lipid infiltration in the heart. The method employs a double-inversion fast spin-echo technique where the acquisition of water- and lipid-suppressed k-space data is alternated between TR periods to produce coregistered lipid and water images from data acquired in a breath hold. The lipid and water images can then be combined to generate a lipid/water image with reduced artifacts due to flow and excellent contrast between lipid and myocardium. The method is demonstrated in ex vivo tissue and in vivo. This novel method may improve the detection of lipid infiltration in the heart in pathologies such as arrhythmogenic right ventricular dysplasia.

AB - In this work we present a new method for the improved detection of lipid infiltration in the heart. The method employs a double-inversion fast spin-echo technique where the acquisition of water- and lipid-suppressed k-space data is alternated between TR periods to produce coregistered lipid and water images from data acquired in a breath hold. The lipid and water images can then be combined to generate a lipid/water image with reduced artifacts due to flow and excellent contrast between lipid and myocardium. The method is demonstrated in ex vivo tissue and in vivo. This novel method may improve the detection of lipid infiltration in the heart in pathologies such as arrhythmogenic right ventricular dysplasia.

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KW - Cardiac

KW - Fast spin echo

KW - Lipid

KW - MRI

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Interleaved acquisition of lipid and water images of the heart using a double-inversion fast spin-echo method

Abstract

Keywords

ASJC Scopus subject areas

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