Interference with testicular development by Δ9 tetrahydrocannabinol

J. W. Harmon; D. Locke; M. A. Aliapoulios; J. H. MacIndoe

Interference with testicular development by Δ⁹ tetrahydrocannabinol

J. W. Harmon, D. Locke, M. A. Aliapoulios, J. H. MacIndoe

Research output: Contribution to journal › Article › peer-review

Abstract

The effect of Δ⁹ tetrahydrocannabinol (THC), the psychoactive ingredient of marihuana, on the testicular development of rats was studied in 48 Walter Reed rats assigned to three groups. Histologic examinations revealed arrest of spermatogenesis in two of the THC treated animals, with normal appearing spermatogenesis in all other animals. The two THC treated rats with arrested spermatogenesis had elevated follicle stimulating hormone (FSH) values of 803 and 660 ng/ml, respectively.

Original language	English (US)
Pages (from-to)	350-352
Number of pages	3
Journal	Surgical forum
Volume	Vol. 27
State	Published - 1976
Externally published	Yes

ASJC Scopus subject areas

Surgery

Cite this

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title = "Interference with testicular development by Δ9 tetrahydrocannabinol",

abstract = "The effect of Δ9 tetrahydrocannabinol (THC), the psychoactive ingredient of marihuana, on the testicular development of rats was studied in 48 Walter Reed rats assigned to three groups. Histologic examinations revealed arrest of spermatogenesis in two of the THC treated animals, with normal appearing spermatogenesis in all other animals. The two THC treated rats with arrested spermatogenesis had elevated follicle stimulating hormone (FSH) values of 803 and 660 ng/ml, respectively.",

author = "Harmon, {J. W.} and D. Locke and Aliapoulios, {M. A.} and MacIndoe, {J. H.}",

year = "1976",

language = "English (US)",

volume = "Vol. 27",

pages = "350--352",

journal = "Surgical forum",

issn = "0071-8041",

publisher = "American College of Surgeons",

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T1 - Interference with testicular development by Δ9 tetrahydrocannabinol

AU - Harmon, J. W.

AU - Locke, D.

AU - Aliapoulios, M. A.

AU - MacIndoe, J. H.

PY - 1976

Y1 - 1976

N2 - The effect of Δ9 tetrahydrocannabinol (THC), the psychoactive ingredient of marihuana, on the testicular development of rats was studied in 48 Walter Reed rats assigned to three groups. Histologic examinations revealed arrest of spermatogenesis in two of the THC treated animals, with normal appearing spermatogenesis in all other animals. The two THC treated rats with arrested spermatogenesis had elevated follicle stimulating hormone (FSH) values of 803 and 660 ng/ml, respectively.

AB - The effect of Δ9 tetrahydrocannabinol (THC), the psychoactive ingredient of marihuana, on the testicular development of rats was studied in 48 Walter Reed rats assigned to three groups. Histologic examinations revealed arrest of spermatogenesis in two of the THC treated animals, with normal appearing spermatogenesis in all other animals. The two THC treated rats with arrested spermatogenesis had elevated follicle stimulating hormone (FSH) values of 803 and 660 ng/ml, respectively.

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AN - SCOPUS:0017092554

SN - 0071-8041

VL - Vol. 27

SP - 350

EP - 352

JO - Surgical forum

JF - Surgical forum

ER -

Interference with testicular development by Δ⁹ tetrahydrocannabinol

Abstract

ASJC Scopus subject areas

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