Abstract
Objective Challenges and barriers continue to hinder the integration of palliative care models into comprehensive, ambulatory oncology care. This article aims to describe how symptoms, distress, and quality of life (QOL) data from the usual care phase of a National Cancer Institute-supported Program Project informed the development of an interdisciplinary, tailored palliative care intervention for patients with metastatic non-small-cell lung cancer (NSCLC). Methods Patients receiving usual care for metastatic NSCLC were recruited into this prospective longitudinal study over a 1-year period. A total of 130 patients with stage IV NSCLC were accrued, and 114 patients had evaluable data. Research nurses assisted patients in completing the clinical section of the data forms, and patients completed surveys and self-reports at baseline and 6, 12, and 24 weeks. Results Patients ranged in age from 40 to 84 years, and 61% were Caucasian non-Hispanic. Sixty-six former (N = 59) and current smokers had an average of 38 pack-year history of smoking. The Karnofsky Performance Status, Instrumental Activities of Daily Living, and Cognitive scores deteriorated significantly (P =.001,.009, and.042, respectively). Social Activity was stable, whereas Social Support increased significantly. Overall symptom distress score and Total symptom score both significantly increased at 24 weeks (P =.003 and.017, respectively). Physical Well-Being decreased significantly (P =.036), whereas the Functional Assessment of Cancer Therapy-Lung, Functional Assessment of Chronic Illness Therapy-Spirituality Subscale, and Distress scores remained statistically stable over time. Conclusions Patients with metastatic NSCLC continue to experience high symptom burden and diminished physical well-being over time while receiving cancer treatments. An interdisciplinary palliative care intervention is currently being tested to improve symptom burden and overall QOL.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 736-744 |
| Number of pages | 9 |
| Journal | Clinical Lung Cancer |
| Volume | 14 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 1 2013 |
| Externally published | Yes |
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Keywords
- Cognition
- Function
- Quality of Life
- Social support
- Symptoms
ASJC Scopus subject areas
- Oncology
- Pulmonary and Respiratory Medicine
- Cancer Research
Cite this
Interdisciplinary palliative care intervention in metastatic non-small-cell lung cancer. / Koczywas, Marianna; Cristea, Mihaela; Thomas, Jay; McCarty, Cassie; Borneman, Tami; Del Ferraro, Catherine; Sun, Virginia; Uman, Gwen; Ferrell, Betty.
In: Clinical Lung Cancer, Vol. 14, No. 6, 01.11.2013, p. 736-744.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interdisciplinary palliative care intervention in metastatic non-small-cell lung cancer
AU - Koczywas, Marianna
AU - Cristea, Mihaela
AU - Thomas, Jay
AU - McCarty, Cassie
AU - Borneman, Tami
AU - Del Ferraro, Catherine
AU - Sun, Virginia
AU - Uman, Gwen
AU - Ferrell, Betty
PY - 2013/11/1
Y1 - 2013/11/1
N2 - Objective Challenges and barriers continue to hinder the integration of palliative care models into comprehensive, ambulatory oncology care. This article aims to describe how symptoms, distress, and quality of life (QOL) data from the usual care phase of a National Cancer Institute-supported Program Project informed the development of an interdisciplinary, tailored palliative care intervention for patients with metastatic non-small-cell lung cancer (NSCLC). Methods Patients receiving usual care for metastatic NSCLC were recruited into this prospective longitudinal study over a 1-year period. A total of 130 patients with stage IV NSCLC were accrued, and 114 patients had evaluable data. Research nurses assisted patients in completing the clinical section of the data forms, and patients completed surveys and self-reports at baseline and 6, 12, and 24 weeks. Results Patients ranged in age from 40 to 84 years, and 61% were Caucasian non-Hispanic. Sixty-six former (N = 59) and current smokers had an average of 38 pack-year history of smoking. The Karnofsky Performance Status, Instrumental Activities of Daily Living, and Cognitive scores deteriorated significantly (P =.001,.009, and.042, respectively). Social Activity was stable, whereas Social Support increased significantly. Overall symptom distress score and Total symptom score both significantly increased at 24 weeks (P =.003 and.017, respectively). Physical Well-Being decreased significantly (P =.036), whereas the Functional Assessment of Cancer Therapy-Lung, Functional Assessment of Chronic Illness Therapy-Spirituality Subscale, and Distress scores remained statistically stable over time. Conclusions Patients with metastatic NSCLC continue to experience high symptom burden and diminished physical well-being over time while receiving cancer treatments. An interdisciplinary palliative care intervention is currently being tested to improve symptom burden and overall QOL.
AB - Objective Challenges and barriers continue to hinder the integration of palliative care models into comprehensive, ambulatory oncology care. This article aims to describe how symptoms, distress, and quality of life (QOL) data from the usual care phase of a National Cancer Institute-supported Program Project informed the development of an interdisciplinary, tailored palliative care intervention for patients with metastatic non-small-cell lung cancer (NSCLC). Methods Patients receiving usual care for metastatic NSCLC were recruited into this prospective longitudinal study over a 1-year period. A total of 130 patients with stage IV NSCLC were accrued, and 114 patients had evaluable data. Research nurses assisted patients in completing the clinical section of the data forms, and patients completed surveys and self-reports at baseline and 6, 12, and 24 weeks. Results Patients ranged in age from 40 to 84 years, and 61% were Caucasian non-Hispanic. Sixty-six former (N = 59) and current smokers had an average of 38 pack-year history of smoking. The Karnofsky Performance Status, Instrumental Activities of Daily Living, and Cognitive scores deteriorated significantly (P =.001,.009, and.042, respectively). Social Activity was stable, whereas Social Support increased significantly. Overall symptom distress score and Total symptom score both significantly increased at 24 weeks (P =.003 and.017, respectively). Physical Well-Being decreased significantly (P =.036), whereas the Functional Assessment of Cancer Therapy-Lung, Functional Assessment of Chronic Illness Therapy-Spirituality Subscale, and Distress scores remained statistically stable over time. Conclusions Patients with metastatic NSCLC continue to experience high symptom burden and diminished physical well-being over time while receiving cancer treatments. An interdisciplinary palliative care intervention is currently being tested to improve symptom burden and overall QOL.
KW - Cognition
KW - Function
KW - Quality of Life
KW - Social support
KW - Symptoms
UR - http://www.scopus.com/inward/record.url?scp=84887215989&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887215989&partnerID=8YFLogxK
U2 - 10.1016/j.cllc.2013.06.008
DO - 10.1016/j.cllc.2013.06.008
M3 - Article
C2 - 23871439
AN - SCOPUS:84887215989
VL - 14
SP - 736
EP - 744
JO - Clinical Lung Cancer
JF - Clinical Lung Cancer
SN - 1525-7304
IS - 6
ER -