Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: A novel pathway for cancer chemoprevention

Medicine & Life Sciences

• oltipraz 88%
• Chemoprevention 58%
• Cytochromes c 56%
• Tuberculin 31%
• Pharmaceutical Preparations 21%
• Neoplasms 16%
• 4-phenylenediamine peroxidase 11%
• Heme 11%
• Thiones 9%
• Iron 8%
• Mitochondria 8%
• Enzymes 8%
• hexacyanoferrate III 8%
• Reactive Oxygen Species 8%
• Spin Trapping 8%
• Temperature 7%
• Electron Transport 5%
• Oxidants 5%
• Superoxides 5%
• Peroxidase 5%
• Oxidation-Reduction 5%
• Cell Death 3%
• Antioxidants 3%

Chemical Compounds

• Oltipraz 100%
• Cancer Chemopreventive 80%
• Cytochrome 45%
• Drug 27%
• Inducer 12%
• Pyrrolopyrazine 10%
• Reactive Oxygen Metabolite 9%
• Heme 9%
• Peroxidase 9%
• EPR Spectroscopy 9%
• Ultraviolet Spectrum 8%
• Spin Trapping 6%
• Apoptotic 6%
• Redox State 5%
• Ferricyanide 5%
• Oxidant Agent 5%
• Cell Death 5%
• Reduction 4%
• Antioxidant Agent 3%
• Environment 2%
• Modification 2%
• Ambient Reaction Temperature 2%
• Time 1%