Viral and bacterial agents may interact in the pathogenesis of disease. Sendai virus is the prime example of an infection of the rodent respiratory tract which may be complicated by a concomitant bacterial infection. These secondary bacterial complications often increase the symptoms and even the mortality rate from those of the primary viral disease. This paper reviews the literature of experimental Sendai virus infection in the murine lung focusing specifically on the synergistic interaction between the virus and bacterial agents and the basic cellular mechanisms by which Sendai virus lowers host resistance and paves the way to secondary bacterial infections.
|Original language||English (US)|
|Number of pages||8|
|Journal||Laboratory animal science|
|State||Published - Dec 1 1981|
ASJC Scopus subject areas
- Animal Science and Zoology