Intensified short symptom screening program for dengue infection during pregnancy, India

Shilpa Naik, Matthew L. Robinson, Mallika Alexander, Ajay Chandanwale, Pradip Sambarey, Aarti Kinikar, Renu Bharadwaj, Gajanan N. Sapkal, Puja Chebrolu, Prasad Deshpande, Vandana Kulkarni, Smita Nimkar, Vidya Mave, Amita Gupta, Jyoti Mathad

Research output: Contribution to journalArticlepeer-review

Abstract

Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017–January 2018, we screened pregnant women during antenatal surveillance for symptoms of mosquitoborne diseases (fever only, fever with conjunctivitis, fever with rash, or all 3 symptoms) within the previous 15 days. Of 5,843 pregnant women screened, 52 were enrolled and tested for dengue, chikungunya, and Zika viruses by using a Trioplex real-time reverse transcription PCR. Of 49 who had complete results, 7 (14%) were dengue positive. Of these, ocular pain was seen in 4 (57%) and conjunctivitis in 7 (100%). Intensified symptom screening using conjunctivitis, in addition to rash, in pregnant women with fever might improve dengue case detection and can be included in routine symptom screening during pregnancy.

Original languageEnglish (US)
Pages (from-to)738-743
Number of pages6
JournalEmerging infectious diseases
Volume26
Issue number4
DOIs
StatePublished - Apr 2020

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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