Intellectual and adaptive functioning in Sturge-Weber Syndrome

Brian Kavanaugh, Aditya Sreenivasan, Catherine Bachur, Aimilia Papazoglou, Anne Comi, T. Andrew Zabel

Research output: Contribution to journalArticle

Abstract

The present study examined the intellectual and adaptive functioning in a sample of children and young adults with Sturge-Weber Syndrome (SWS). A total of 80 research participants from a SWS study database underwent full neurological evaluation as part of their participation or concurrent medical care. Twenty-nine of the participants received neuropsychological evaluations. Analyses indicated no significant demographic or neurological differences between those who did and did not receive neuropsychological evaluations. Overall, the neuropsychological evaluation sample displayed significantly lower functioning relative to published normative data across domains of intellectual and adaptive functioning. Thirty-two percent of the sample displayed impaired performance (standard score ≤ 75) in intellectual functioning and 58% displayed impaired performance in adaptive functioning. Hemiparesis status independently predicted overall adaptive functioning while seizure frequency independently predicted overall intellectual functioning. Younger participants displayed significantly higher (more intact) ratings in adaptive functioning compared to older participants, specifically in overall adaptive functioning, motor skills, and community living skills. A composite measure of neurological status (SWS-NRS) incorporating seizure and hemiparesis status effectively distinguished between individuals with impaired or nonimpaired adaptive and intellectual functioning and showed promise as a screening method for identifying individuals with more involved intellectual and/or adaptive needs.

Original languageEnglish (US)
JournalChild Neuropsychology
DOIs
StateAccepted/In press - May 3 2015

Fingerprint

Sturge-Weber Syndrome
Paresis
Seizures
Motor Skills
Young Adult
Demography

Keywords

  • Adaptive function
  • Intelligence
  • Neurology
  • Neuropsychology
  • Sturge-Weber Syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Intellectual and adaptive functioning in Sturge-Weber Syndrome. / Kavanaugh, Brian; Sreenivasan, Aditya; Bachur, Catherine; Papazoglou, Aimilia; Comi, Anne; Zabel, T. Andrew.

In: Child Neuropsychology, 03.05.2015.

Research output: Contribution to journalArticle

Kavanaugh B, Sreenivasan A, Bachur C, Papazoglou A, Comi A, Zabel TA. Intellectual and adaptive functioning in Sturge-Weber Syndrome. Child Neuropsychology. 2015 May 3. Available from, DOI: 10.1080/09297049.2015.1028349

Kavanaugh, Brian; Sreenivasan, Aditya; Bachur, Catherine; Papazoglou, Aimilia; Comi, Anne; Zabel, T. Andrew / Intellectual and adaptive functioning in Sturge-Weber Syndrome.

In: Child Neuropsychology, 03.05.2015.

Research output: Contribution to journalArticle

@article{f50dbf18c86b4ca592b23f61b84b4313,
title = "Intellectual and adaptive functioning in Sturge-Weber Syndrome",
abstract = "The present study examined the intellectual and adaptive functioning in a sample of children and young adults with Sturge-Weber Syndrome (SWS). A total of 80 research participants from a SWS study database underwent full neurological evaluation as part of their participation or concurrent medical care. Twenty-nine of the participants received neuropsychological evaluations. Analyses indicated no significant demographic or neurological differences between those who did and did not receive neuropsychological evaluations. Overall, the neuropsychological evaluation sample displayed significantly lower functioning relative to published normative data across domains of intellectual and adaptive functioning. Thirty-two percent of the sample displayed impaired performance (standard score ≤ 75) in intellectual functioning and 58% displayed impaired performance in adaptive functioning. Hemiparesis status independently predicted overall adaptive functioning while seizure frequency independently predicted overall intellectual functioning. Younger participants displayed significantly higher (more intact) ratings in adaptive functioning compared to older participants, specifically in overall adaptive functioning, motor skills, and community living skills. A composite measure of neurological status (SWS-NRS) incorporating seizure and hemiparesis status effectively distinguished between individuals with impaired or nonimpaired adaptive and intellectual functioning and showed promise as a screening method for identifying individuals with more involved intellectual and/or adaptive needs.",
keywords = "Adaptive function, Intelligence, Neurology, Neuropsychology, Sturge-Weber Syndrome",
author = "Brian Kavanaugh and Aditya Sreenivasan and Catherine Bachur and Aimilia Papazoglou and Anne Comi and Zabel, {T. Andrew}",
year = "2015",
month = "5",
doi = "10.1080/09297049.2015.1028349",
journal = "Child Neuropsychology",
issn = "0929-7049",
publisher = "Psychology Press Ltd",

}

TY - JOUR

T1 - Intellectual and adaptive functioning in Sturge-Weber Syndrome

AU - Kavanaugh,Brian

AU - Sreenivasan,Aditya

AU - Bachur,Catherine

AU - Papazoglou,Aimilia

AU - Comi,Anne

AU - Zabel,T. Andrew

PY - 2015/5/3

Y1 - 2015/5/3

N2 - The present study examined the intellectual and adaptive functioning in a sample of children and young adults with Sturge-Weber Syndrome (SWS). A total of 80 research participants from a SWS study database underwent full neurological evaluation as part of their participation or concurrent medical care. Twenty-nine of the participants received neuropsychological evaluations. Analyses indicated no significant demographic or neurological differences between those who did and did not receive neuropsychological evaluations. Overall, the neuropsychological evaluation sample displayed significantly lower functioning relative to published normative data across domains of intellectual and adaptive functioning. Thirty-two percent of the sample displayed impaired performance (standard score ≤ 75) in intellectual functioning and 58% displayed impaired performance in adaptive functioning. Hemiparesis status independently predicted overall adaptive functioning while seizure frequency independently predicted overall intellectual functioning. Younger participants displayed significantly higher (more intact) ratings in adaptive functioning compared to older participants, specifically in overall adaptive functioning, motor skills, and community living skills. A composite measure of neurological status (SWS-NRS) incorporating seizure and hemiparesis status effectively distinguished between individuals with impaired or nonimpaired adaptive and intellectual functioning and showed promise as a screening method for identifying individuals with more involved intellectual and/or adaptive needs.

AB - The present study examined the intellectual and adaptive functioning in a sample of children and young adults with Sturge-Weber Syndrome (SWS). A total of 80 research participants from a SWS study database underwent full neurological evaluation as part of their participation or concurrent medical care. Twenty-nine of the participants received neuropsychological evaluations. Analyses indicated no significant demographic or neurological differences between those who did and did not receive neuropsychological evaluations. Overall, the neuropsychological evaluation sample displayed significantly lower functioning relative to published normative data across domains of intellectual and adaptive functioning. Thirty-two percent of the sample displayed impaired performance (standard score ≤ 75) in intellectual functioning and 58% displayed impaired performance in adaptive functioning. Hemiparesis status independently predicted overall adaptive functioning while seizure frequency independently predicted overall intellectual functioning. Younger participants displayed significantly higher (more intact) ratings in adaptive functioning compared to older participants, specifically in overall adaptive functioning, motor skills, and community living skills. A composite measure of neurological status (SWS-NRS) incorporating seizure and hemiparesis status effectively distinguished between individuals with impaired or nonimpaired adaptive and intellectual functioning and showed promise as a screening method for identifying individuals with more involved intellectual and/or adaptive needs.

KW - Adaptive function

KW - Intelligence

KW - Neurology

KW - Neuropsychology

KW - Sturge-Weber Syndrome

UR - http://www.scopus.com/inward/record.url?scp=84929011807&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929011807&partnerID=8YFLogxK

U2 - 10.1080/09297049.2015.1028349

DO - 10.1080/09297049.2015.1028349

M3 - Article

JO - Child Neuropsychology

T2 - Child Neuropsychology

JF - Child Neuropsychology

SN - 0929-7049

ER -