Integrative models for understanding the structural basis of regional mechanical dysfunction in ischemic myocardium

Reza Mazhari, Andrew D. McCulloch

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

The regional flow-function relation can be influenced by mechanical interactions. A review is presented that demonstrates the necessity of accounting for three-dimensional (3D) mechanics of the ventricle in order to interpret the cellular basis of regional dysfunction in complex regional disorders such as ischemia and stunning.

Original languageEnglish (US)
Pages (from-to)979-990
Number of pages12
JournalAnnals of Biomedical Engineering
Volume28
Issue number8
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Biomedical Engineering

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