Integration of structure, function and mass transport in the myocardium

D. Zinemanas; R. Beyar; S. Sideman; T. Arts; H. E D J Ter Keurs; J. Bassingthwaighte; Y. Lanir

Integration of structure, function and mass transport in the myocardium

D. Zinemanas, R. Beyar, S. Sideman, T. Arts, H. E D J Ter Keurs, J. Bassingthwaighte, Y. Lanir

Research output: Contribution to journal › Article › peer-review

Abstract

A left ventricular (LV) model that integrates muscle mechanics, coronary flow, and fluid transport, and accounts for the three-phase (fiber-blood- interstitium) myocardial structure and composition, is used to study the interactions between the mechanics, coronary flow and fluid and mass transport in the myocardium. Theoretical simulations elucidate the effects of ventricular load, coronary perfusion pressure, and fluid and mass transport on ventricular performance and coronary dynamics. The analysis yields a direct relation between cardiac function and structure to cardiac mechanics, coronary flow, and intramyocardial fluid (and mass) transport, and allows to study the interactions between coronary flow, ventricular and myocardial mechanics and intramyocardial fluid shifts.

Original language	English (US)
Pages (from-to)	279-292
Number of pages	14
Journal	Advances in Experimental Medicine and Biology
Volume	382
State	Published - 1995
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Cite this

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author = "D. Zinemanas and R. Beyar and S. Sideman and T. Arts and {Ter Keurs}, {H. E D J} and J. Bassingthwaighte and Y. Lanir",

year = "1995",

language = "English (US)",

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journal = "Advances in Experimental Medicine and Biology",

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T1 - Integration of structure, function and mass transport in the myocardium

AU - Zinemanas, D.

AU - Beyar, R.

AU - Sideman, S.

AU - Arts, T.

AU - Ter Keurs, H. E D J

AU - Bassingthwaighte, J.

AU - Lanir, Y.

PY - 1995

Y1 - 1995

N2 - A left ventricular (LV) model that integrates muscle mechanics, coronary flow, and fluid transport, and accounts for the three-phase (fiber-blood- interstitium) myocardial structure and composition, is used to study the interactions between the mechanics, coronary flow and fluid and mass transport in the myocardium. Theoretical simulations elucidate the effects of ventricular load, coronary perfusion pressure, and fluid and mass transport on ventricular performance and coronary dynamics. The analysis yields a direct relation between cardiac function and structure to cardiac mechanics, coronary flow, and intramyocardial fluid (and mass) transport, and allows to study the interactions between coronary flow, ventricular and myocardial mechanics and intramyocardial fluid shifts.

AB - A left ventricular (LV) model that integrates muscle mechanics, coronary flow, and fluid transport, and accounts for the three-phase (fiber-blood- interstitium) myocardial structure and composition, is used to study the interactions between the mechanics, coronary flow and fluid and mass transport in the myocardium. Theoretical simulations elucidate the effects of ventricular load, coronary perfusion pressure, and fluid and mass transport on ventricular performance and coronary dynamics. The analysis yields a direct relation between cardiac function and structure to cardiac mechanics, coronary flow, and intramyocardial fluid (and mass) transport, and allows to study the interactions between coronary flow, ventricular and myocardial mechanics and intramyocardial fluid shifts.

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M3 - Article

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AN - SCOPUS:0029116590

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VL - 382

SP - 279

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JO - Advances in Experimental Medicine and Biology

JF - Advances in Experimental Medicine and Biology

ER -

Integration of structure, function and mass transport in the myocardium

Abstract

ASJC Scopus subject areas

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