Integration of nutritional support with paediatric HIV care in developing countries

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Abstract

Human immunodeficiency virus (HIV) infection and malnutrition remain major causes of morbidity and mortality among children in developing countries. Malnutrition also exacerbates the clinical course of HIV-infected children by further compromising immunity and increasing the severity of opportunistic infections. This review summarizes current scientific knowledge regarding the role of nutrition in the pathophysiology of HIV infection in children and presents the perspective of integrating nutritional interventions with programmes in resource-limited settings to increase survival of HIV-exposed and -infected children. The three major programming areas for identifying and caring for HIV-infected and HIV-exposed children are: (1) prevention of mother-to-child transmission (PMTCT) of HIV, which is the earliest possible detection of HIV-exposure of the child, (2) care for HIV-infected children and (3) treatment of malnourished children, as for many children whose HIV exposure is unknown, malnutrition can be a first sign of HIV infection. Care for HIV-exposed and -infected infants and children requires early diagnosis of HIV exposure and status, especially through PMTCT services, availability of antiretrovirals (ARVs) and nutritional services including growth monitoring, use of specially formulated foods, micronutrient supplementation, vitamin A supplementation, zinc therapy and micronutrient supplementation for the treatment of diarrhoea, use of iodized salt and exclusive breastfeeding according to national guidelines. Given that the scale-up of PMTCT is expected to accelerate in the next several years, basic nutritional interventions should be part of the standard of care of these programmes.

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Nutritional Support
nutritional support
Human immunodeficiency virus
human immunodeficiency virus
Developing Countries
developing countries
developing world
HIV
Pediatrics
malnutrition
Virus Diseases
HIV infections
Malnutrition
Micronutrients
Mothers
nutritional intervention
dietary minerals
trace element
iodized salt
Formulated Food

Keywords

  • Acquired immune deficiency syndrome
  • Children
  • Food
  • Human immunodeficiency virus
  • Malnutrition
  • Micronutrient
  • Nutrition

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Nature and Landscape Conservation
  • veterinary(all)

Cite this

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title = "Integration of nutritional support with paediatric HIV care in developing countries",
abstract = "Human immunodeficiency virus (HIV) infection and malnutrition remain major causes of morbidity and mortality among children in developing countries. Malnutrition also exacerbates the clinical course of HIV-infected children by further compromising immunity and increasing the severity of opportunistic infections. This review summarizes current scientific knowledge regarding the role of nutrition in the pathophysiology of HIV infection in children and presents the perspective of integrating nutritional interventions with programmes in resource-limited settings to increase survival of HIV-exposed and -infected children. The three major programming areas for identifying and caring for HIV-infected and HIV-exposed children are: (1) prevention of mother-to-child transmission (PMTCT) of HIV, which is the earliest possible detection of HIV-exposure of the child, (2) care for HIV-infected children and (3) treatment of malnourished children, as for many children whose HIV exposure is unknown, malnutrition can be a first sign of HIV infection. Care for HIV-exposed and -infected infants and children requires early diagnosis of HIV exposure and status, especially through PMTCT services, availability of antiretrovirals (ARVs) and nutritional services including growth monitoring, use of specially formulated foods, micronutrient supplementation, vitamin A supplementation, zinc therapy and micronutrient supplementation for the treatment of diarrhoea, use of iodized salt and exclusive breastfeeding according to national guidelines. Given that the scale-up of PMTCT is expected to accelerate in the next several years, basic nutritional interventions should be part of the standard of care of these programmes.",
keywords = "Acquired immune deficiency syndrome, Children, Food, Human immunodeficiency virus, Malnutrition, Micronutrient, Nutrition",
author = "Semba, {Richard David} and {De Pee}, Saskia and Martin Bloem",
year = "2012",
doi = "10.1079/PAVSNNR20127057",
language = "English (US)",
volume = "7",
journal = "CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources",
issn = "1749-8848",
publisher = "CAB International",

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T1 - Integration of nutritional support with paediatric HIV care in developing countries

AU - Semba, Richard David

AU - De Pee, Saskia

AU - Bloem, Martin

PY - 2012

Y1 - 2012

N2 - Human immunodeficiency virus (HIV) infection and malnutrition remain major causes of morbidity and mortality among children in developing countries. Malnutrition also exacerbates the clinical course of HIV-infected children by further compromising immunity and increasing the severity of opportunistic infections. This review summarizes current scientific knowledge regarding the role of nutrition in the pathophysiology of HIV infection in children and presents the perspective of integrating nutritional interventions with programmes in resource-limited settings to increase survival of HIV-exposed and -infected children. The three major programming areas for identifying and caring for HIV-infected and HIV-exposed children are: (1) prevention of mother-to-child transmission (PMTCT) of HIV, which is the earliest possible detection of HIV-exposure of the child, (2) care for HIV-infected children and (3) treatment of malnourished children, as for many children whose HIV exposure is unknown, malnutrition can be a first sign of HIV infection. Care for HIV-exposed and -infected infants and children requires early diagnosis of HIV exposure and status, especially through PMTCT services, availability of antiretrovirals (ARVs) and nutritional services including growth monitoring, use of specially formulated foods, micronutrient supplementation, vitamin A supplementation, zinc therapy and micronutrient supplementation for the treatment of diarrhoea, use of iodized salt and exclusive breastfeeding according to national guidelines. Given that the scale-up of PMTCT is expected to accelerate in the next several years, basic nutritional interventions should be part of the standard of care of these programmes.

AB - Human immunodeficiency virus (HIV) infection and malnutrition remain major causes of morbidity and mortality among children in developing countries. Malnutrition also exacerbates the clinical course of HIV-infected children by further compromising immunity and increasing the severity of opportunistic infections. This review summarizes current scientific knowledge regarding the role of nutrition in the pathophysiology of HIV infection in children and presents the perspective of integrating nutritional interventions with programmes in resource-limited settings to increase survival of HIV-exposed and -infected children. The three major programming areas for identifying and caring for HIV-infected and HIV-exposed children are: (1) prevention of mother-to-child transmission (PMTCT) of HIV, which is the earliest possible detection of HIV-exposure of the child, (2) care for HIV-infected children and (3) treatment of malnourished children, as for many children whose HIV exposure is unknown, malnutrition can be a first sign of HIV infection. Care for HIV-exposed and -infected infants and children requires early diagnosis of HIV exposure and status, especially through PMTCT services, availability of antiretrovirals (ARVs) and nutritional services including growth monitoring, use of specially formulated foods, micronutrient supplementation, vitamin A supplementation, zinc therapy and micronutrient supplementation for the treatment of diarrhoea, use of iodized salt and exclusive breastfeeding according to national guidelines. Given that the scale-up of PMTCT is expected to accelerate in the next several years, basic nutritional interventions should be part of the standard of care of these programmes.

KW - Acquired immune deficiency syndrome

KW - Children

KW - Food

KW - Human immunodeficiency virus

KW - Malnutrition

KW - Micronutrient

KW - Nutrition

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