Integration of free-hand 3D ultrasound and mobile C-arm cone-beam CT: Feasibility and characterization for real-time guidance of needle insertion

E. Marinetto, A. Uneri, T. De Silva, S. Reaungamornrat, W. Zbijewski, A. Sisniega, S. Vogt, G. Kleinszig, J. Pascau, J. H. Siewerdsen

Research output: Contribution to journalArticlepeer-review

Abstract

This work presents development of an integrated ultrasound (US)–cone-beam CT (CBCT) system for image-guided needle interventions, combining a low-cost ultrasound system (Interson VC 7.5 MHz, Pleasanton, CA) with a mobile C-arm for fluoroscopy and CBCT via use of a surgical tracker. Imaging performance of the ultrasound system was characterized in terms of depth-dependent contrast-to-noise ratio (CNR) and spatial resolution. US–CBCT system was evaluated in phantom studies simulating three needle-based procedures: drug delivery, tumor ablation, and lumbar puncture. Low-cost ultrasound provided flexibility but exhibited modest CNR and spatial resolution that is likely limited to fairly superficial applications within a ∼10 cm depth of view. Needle tip localization demonstrated target registration error 2.1–3.0 mm using fiducial-based registration.

Original languageEnglish (US)
Pages (from-to)13-22
Number of pages10
JournalComputerized Medical Imaging and Graphics
Volume58
DOIs
StatePublished - Jun 1 2017

Keywords

  • C-arm imaging
  • Cone-beam CT
  • Image-guided procedures
  • Target registration error
  • Ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design

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