Integration of coronary anatomy, perfusion and metabolism: Three-dimensional image fusion of coronary angiography and nuclear cardiac imaging

Nobuhisa Magosaki, T. H. Schindler, R. Fischer, T. Krause, E. Nitzsche, M. Zehender, E. Moser, H. Just

Research output: Contribution to journalConference article

Abstract

We studied three-dimensional (3D) fusion imaging that enabled the integration of coronary anatomy, perfusion and metabolic image on the patient-specific 3D left ventricle. In 36 patients with coronary artery disease, 420 coronary branches, including 46 branches supplied by collateral, were reconstructed (12 branches/patient). One hundred coronary branches had high-grade stenoses (>80%), 35% and 39% showed reversible and irreversible perfusion defects. Extent of perfusion defects showed good coincidence with the territories of corresponding coronary arteries. Forty-three myocardial regions were considered nonviable by perfusion imaging. Of these 43, 32 showed perfusion metabolism mismatch suggesting myocardial viability. Location and extent of viable myocardium were clearly defined. 3-D fusion imaging enabled assessment of perfusion and metabolic abnormalities of individual vessels on the patient-specific left ventricle.

Original languageEnglish (US)
Pages (from-to)615-618
Number of pages4
JournalComputers in cardiology
StatePublished - Dec 1 1999
EventThe 26th Annual Meeting: Computers in Cardiology 1999 - Hannover, Ger
Duration: Sep 26 1999Sep 29 1999

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

Cite this

Magosaki, N., Schindler, T. H., Fischer, R., Krause, T., Nitzsche, E., Zehender, M., Moser, E., & Just, H. (1999). Integration of coronary anatomy, perfusion and metabolism: Three-dimensional image fusion of coronary angiography and nuclear cardiac imaging. Computers in cardiology, 615-618.