Integration of Brassinosteroid Signal Transduction with the Transcription Network for Plant Growth Regulation in Arabidopsis

Yu Sun, Xi Ying Fan, Dong Mei Cao, Wenqiang Tang, Kun He, Jia Ying Zhu, Jun Xian He, Ming Yi Bai, Shengwei Zhu, Eunkyoo Oh, Sunita Patil, Tae Wuk Kim, Hong Kai Ji, Wing Hong Wong, Seung Y. Rhee, Zhi Yong Wang

Research output: Contribution to journalArticle

Abstract

Brassinosteroids (BRs) regulate a wide range of developmental and physiological processes in plants through a receptor-kinase signaling pathway that controls the BZR transcription factors. Here, we use transcript profiling and chromatin-immunoprecipitation microarray (ChIP-chip) experiments to identify 953 BR-regulated BZR1 target (BRBT) genes. Functional studies of selected BRBTs further demonstrate roles in BR promotion of cell elongation. The BRBT genes reveal numerous molecular links between the BR-signaling pathway and downstream components involved in developmental and physiological processes. Furthermore, the results reveal extensive crosstalk between BR and other hormonal and light-signaling pathways at multiple levels. For example, BZR1 not only controls the expression of many signaling components of other hormonal and light pathways but also coregulates common target genes with light-signaling transcription factors. Our results provide a genomic map of steroid hormone actions in plants that reveals a regulatory network that integrates hormonal and light-signaling pathways for plant growth regulation.

Original languageEnglish (US)
Pages (from-to)765-777
Number of pages13
JournalDevelopmental Cell
Volume19
Issue number5
DOIs
StatePublished - Nov 16 2010
Externally publishedYes

Fingerprint

Brassinosteroids
Signal transduction
Transcription
Arabidopsis
Signal Transduction
Light
Growth
Genes
Transcription Factors
Plant Physiological Phenomena
Physiological Phenomena
Steroid hormones
Chromatin Immunoprecipitation
Microarrays
Crosstalk
Phosphotransferases
Chromatin
Steroids
Elongation
Hormones

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Integration of Brassinosteroid Signal Transduction with the Transcription Network for Plant Growth Regulation in Arabidopsis. / Sun, Yu; Fan, Xi Ying; Cao, Dong Mei; Tang, Wenqiang; He, Kun; Zhu, Jia Ying; He, Jun Xian; Bai, Ming Yi; Zhu, Shengwei; Oh, Eunkyoo; Patil, Sunita; Kim, Tae Wuk; Ji, Hong Kai; Wong, Wing Hong; Rhee, Seung Y.; Wang, Zhi Yong.

In: Developmental Cell, Vol. 19, No. 5, 16.11.2010, p. 765-777.

Research output: Contribution to journalArticle

Sun, Y, Fan, XY, Cao, DM, Tang, W, He, K, Zhu, JY, He, JX, Bai, MY, Zhu, S, Oh, E, Patil, S, Kim, TW, Ji, HK, Wong, WH, Rhee, SY & Wang, ZY 2010, 'Integration of Brassinosteroid Signal Transduction with the Transcription Network for Plant Growth Regulation in Arabidopsis', Developmental Cell, vol. 19, no. 5, pp. 765-777. https://doi.org/10.1016/j.devcel.2010.10.010
Sun, Yu ; Fan, Xi Ying ; Cao, Dong Mei ; Tang, Wenqiang ; He, Kun ; Zhu, Jia Ying ; He, Jun Xian ; Bai, Ming Yi ; Zhu, Shengwei ; Oh, Eunkyoo ; Patil, Sunita ; Kim, Tae Wuk ; Ji, Hong Kai ; Wong, Wing Hong ; Rhee, Seung Y. ; Wang, Zhi Yong. / Integration of Brassinosteroid Signal Transduction with the Transcription Network for Plant Growth Regulation in Arabidopsis. In: Developmental Cell. 2010 ; Vol. 19, No. 5. pp. 765-777.
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