Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

Clinical Proteomic Tumor Analysis Consortium

Research output: Contribution to journalArticle

Abstract

Comprehensive proteogenomic characterization in 103 treatment-naive clear cell renal cell carcinoma patient samples highlights tumor-specific alterations at the proteomic level that are unrevealed by transcriptomic profiling and proposes a revised subtyping scheme based on integrated omics analysis.

Original languageEnglish (US)
Pages (from-to)964-983.e31
JournalCell
Volume179
Issue number4
DOIs
StatePublished - Oct 31 2019

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Keywords

  • ccRCC
  • chromosomal translocation
  • CPTAC
  • drug targets
  • immune infiltration
  • phosphoproteomics
  • proteogenomics
  • proteomics
  • renal carcinoma
  • tumor microenvironment

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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