Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

Clinical Proteomic Tumor Analysis Consortium

Research output: Contribution to journalArticle

Abstract

Comprehensive proteogenomic characterization in 103 treatment-naive clear cell renal cell carcinoma patient samples highlights tumor-specific alterations at the proteomic level that are unrevealed by transcriptomic profiling and proposes a revised subtyping scheme based on integrated omics analysis.

Original languageEnglish (US)
Pages (from-to)964-983.e31
JournalCell
Volume179
Issue number4
DOIs
StatePublished - Oct 31 2019

Fingerprint

Renal Cell Carcinoma
Proteomics
Cells
Tumors
Neoplasms
Therapeutics
Proteogenomics

Keywords

  • ccRCC
  • chromosomal translocation
  • CPTAC
  • drug targets
  • immune infiltration
  • phosphoproteomics
  • proteogenomics
  • proteomics
  • renal carcinoma
  • tumor microenvironment

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. / Clinical Proteomic Tumor Analysis Consortium.

In: Cell, Vol. 179, No. 4, 31.10.2019, p. 964-983.e31.

Research output: Contribution to journalArticle

Clinical Proteomic Tumor Analysis Consortium 2019, 'Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma', Cell, vol. 179, no. 4, pp. 964-983.e31. https://doi.org/10.1016/j.cell.2019.10.007
Clinical Proteomic Tumor Analysis Consortium. Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. Cell. 2019 Oct 31;179(4):964-983.e31. https://doi.org/10.1016/j.cell.2019.10.007
Clinical Proteomic Tumor Analysis Consortium. / Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. In: Cell. 2019 ; Vol. 179, No. 4. pp. 964-983.e31.
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abstract = "Comprehensive proteogenomic characterization in 103 treatment-naive clear cell renal cell carcinoma patient samples highlights tumor-specific alterations at the proteomic level that are unrevealed by transcriptomic profiling and proposes a revised subtyping scheme based on integrated omics analysis.",
keywords = "ccRCC, chromosomal translocation, CPTAC, drug targets, immune infiltration, phosphoproteomics, proteogenomics, proteomics, renal carcinoma, tumor microenvironment",
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