Institutional Responsibility and the Flawed Genomic Biomarkers at Duke University: A Missed Opportunity for Transparency and Accountability

David L. DeMets, Thomas R. Fleming, Gail Geller, David F. Ransohoff

Research output: Contribution to journalArticle

Abstract

When there have been substantial failures by institutional leadership in their oversight responsibility to protect research integrity, the public should demand that these be recognized and addressed by the institution itself, or the funding bodies. This commentary discusses a case of research failures in developing genomic predictors for cancer risk assessment and treatment at a leading university. In its review of this case, the Office of Research Integrity, an agency within the US Department of Health and Human Services, focused their report entirely on one individual faculty member and made no comment on the institution’s responsibility and its failure to provide adequate oversight and investigation. These actions missed an important opportunity to emphasize the institution’s critical responsibilities in oversight of research integrity and the importance of institutional transparency and accountability.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalScience and Engineering Ethics
DOIs
StateAccepted/In press - Nov 23 2016

Keywords

  • Genomic predictors
  • Institutional review
  • Office of Research Integrity
  • Research fraud

ASJC Scopus subject areas

  • Health(social science)
  • Issues, ethics and legal aspects
  • Health Policy
  • Management of Technology and Innovation

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