Insights into adult postlesional language cortical plasticity provided by cerebral blood oxygen level-dependent functional MR imaging

Research output: Contribution to journalReview articlepeer-review

Abstract

BOLD fMRI has provided new insights into postlesional brain language plasticity by providing a noninvasive in vivo approach to evaluate longitudinal changes in brain cortical activation during performance of language tasks. Specifically, BOLD fMRI has provided the opportunity to investigate not only changes in eloquent language cortex resulting from different types of brain pathology such as brain tumors, stroke, and epilepsy but also changes in eloquent language cortex occurring as a result of actual surgical resection of diseased but, nevertheless, partially functional tissue. In addition to reviewing the literature relating to stroke and epilepsy-related language plasticity as well as the more intriguing phenomenon of postsurgical plasticity in the setting of brain tumors, 2 unusual cases illustrating this latter manifestation of language plasticity are briefly described in this review article.

Original languageEnglish (US)
Pages (from-to)990-996
Number of pages7
JournalAmerican Journal of Neuroradiology
Volume31
Issue number6
DOIs
StatePublished - 2010

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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