Insights from Ultrahigh Field Imaging in Multiple Sclerosis

Matthew K. Schindler, Pascal Sati, Daniel S. Reich

Research output: Contribution to journalReview articlepeer-review


Ultrahigh-field (≥7 T) magnetic resonance (MR) imaging is being used at many leading academic medical centers to study neurologic disorders. The improved spatial resolution and anatomic detail are due to the increase in signal-to-noise and contrast-to-noise ratio at higher magnetic field strengths. Ultrahigh-field MR imaging improves multiple sclerosis (MS) lesion detection, with particular sensitivity to detect cortical lesions. The increase in magnetic susceptibility effects inherent to ultrahigh field can be used to detect pathologic features of MS lesions, including a central vein, potentially useful for diagnostic considerations, and heterogeneity among MS lesions, potentially useful in determining lesion outcomes.

Original languageEnglish (US)
Pages (from-to)357-366
Number of pages10
JournalNeuroimaging Clinics of North America
Issue number2
StatePublished - May 1 2017


  • MR imaging
  • Multiple sclerosis
  • Ultrahigh field imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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