Inner retinal vasculopathy in Zika virus disease

Mandeep Singh, Maria Carolina Marquezan, Revaz Omiadze, Ashvini Reddy, Rubens Belfort, William May

Research output: Contribution to journalArticle

Abstract

Purpose: Zika virus infection is associated with vision-threatening ocular complications including uveitis and outer retinopathy. The aim of this report is to describe a case of an adult patient with serologically confirmed Zika infection who presented with retinal vascular abnormalities that coincided with systemic post-viral neurological manifestations of the disease. Observations: A 34-year-old white female presented with symptoms of peripheral neuropathy following serologically confirmed Zika virus infection that was acquired in Puerto Rico four months prior to presentation. Ocular evaluation revealed perifoveal microaneurysms which were not associated with visual symptoms. Conclusions and importance: These data potentially expand the phenotypic spectrum of Zika virus retinopathy. In addition to outer retinal abnormalities which are well-described in infants and adults, inner retinal vascular abnormalities may also occur and may be temporally associated with post-viral neurological sequelae of Zika virus infection. Clinicians should be aware of potential retinal involvement in affected patients who present with neurological symptoms after recovery from acute Zika virus infection.

Original languageEnglish (US)
Pages (from-to)6-7
Number of pages2
JournalAmerican Journal of Ophthalmology Case Reports
Volume10
DOIs
StatePublished - Jun 1 2018

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Retinal Vessels
Puerto Rico
Uveitis
Peripheral Nervous System Diseases
Neurologic Manifestations
Zika Virus Infection
Infection
Zika Virus
Microaneurysm

Keywords

  • Angiography
  • Multimodal imaging
  • Retina
  • Vasculopathy
  • Vision
  • Zika virus

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Inner retinal vasculopathy in Zika virus disease. / Singh, Mandeep; Marquezan, Maria Carolina; Omiadze, Revaz; Reddy, Ashvini; Belfort, Rubens; May, William.

In: American Journal of Ophthalmology Case Reports, Vol. 10, 01.06.2018, p. 6-7.

Research output: Contribution to journalArticle

Singh, Mandeep ; Marquezan, Maria Carolina ; Omiadze, Revaz ; Reddy, Ashvini ; Belfort, Rubens ; May, William. / Inner retinal vasculopathy in Zika virus disease. In: American Journal of Ophthalmology Case Reports. 2018 ; Vol. 10. pp. 6-7.
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