Initiation and termination of spiral waves in a two-dimensional bidomain model of cardiac tissue

Nitish V Thakor, M. G. Fishier

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Spiral waves in cardiac tissue serve as a simplified model of ventricular fibrillation (VF). Initiation and termination of the spiral wave is studied in a computer model. The computer model comprises a two-dimensional, bidomain, discontinuous and anisotropic network of cardiac cells. In an analogous experimental preparation, electrical activity is imaged using a voltage sensitive fluorescent dye. The model and the experiment reproduce similar spiral wave activity. Application of electrical shock of adequate strength, in the model as well as the experiment, eliminated the spiral wave pattern.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
Pages229-232
Number of pages4
Volume0
Edition0
Publication statusPublished - 1996

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ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

Cite this

Thakor, N. V., & Fishier, M. G. (1996). Initiation and termination of spiral waves in a two-dimensional bidomain model of cardiac tissue. In Computers in Cardiology (0 ed., Vol. 0, pp. 229-232)