Initiation and termination of spiral waves in a two-dimensional bidomain model of cardiac tissue

N. V. Thakor, M. G. Fishier

Research output: Contribution to journalArticlepeer-review

Abstract

Spiral waves in cardiac tissue serve as a simplified model of ventricular fibrillation (VF). Initiation and termination of the spiral wave is studied in a computer model. The computer model comprises a two-dimensional, bidomain, discontinuous and anisotropic network of cardiac cells. In an analogous experimental preparation, electrical activity is imaged using a voltage sensitive fluorescent dye. The model and the experiment reproduce similar spiral wave activity. Application of electrical shock of adequate strength, in the model as well as the experiment, eliminated the spiral wave pattern.

Original languageEnglish (US)
Pages (from-to)229-232
Number of pages4
JournalComputers in cardiology
Volume0
Issue number0
StatePublished - Dec 1 1996

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

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