Initial validation of a novel ECGI system for localization of premature ventricular contractions and ventricular tachycardia in structurally normal and abnormal hearts

Satish Misra, Peter van Dam, Jonathan Chrispin, Fabrizio Assis, Ali Keramati, Aravindan Kolandaivelu, Ronald D Berger, Harikrishna Tandri

Research output: Contribution to journalArticle

Abstract

Background: View into Ventricular Onset (VIVO) is a novel ECGI system that uses 3D body surface imaging, myocardial CT/MRI, and 12‑lead ECG to localize earliest ventricular activation through analysis of simulated and clinical vector cardiograms. Objective: To evaluate the accuracy of VIVO for the localization of ventricular arrhythmias (VA). Methods: In twenty patients presenting for catheter ablation of VT [8] or PVC [12], VIVO was used to predict the site earliest activation using 12‑lead ECG of the VA. Results were compared to invasive electroanatomic mapping (EAM). Results: A total of 22 PVC/VT morphologies were analyzed using VIVO. VIVO accurately predicted the location of the VA in 11/13 PVC cases and 8/9 VT cases. VIVO correctly predicted right vs left ventricular foci in 20/22 cases. Conclusion: View into Ventricular Onset (VIVO) can accurately predict earliest activation of VA, which could aid in catheter ablation, and should be studied further.

Original languageEnglish (US)
Pages (from-to)801-808
Number of pages8
JournalJournal of Electrocardiology
Volume51
Issue number5
DOIs
StatePublished - Sep 1 2018

Keywords

  • Electrocardiographic imaging
  • Non-invasive mapping
  • Premature ventricular contractions
  • Vectorcardiography
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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