Initial results on in vivo human coronary MR angiography at 7 T

Saska G.C. Van Elderen, Maarten J. Versluis, Andrew G. Webb, Jos J.M. Westenberg, Joost Doornbos, Nadine B. Smith, Albert De Roos, Matthias Stuber

Research output: Contribution to journalArticlepeer-review

Abstract

Seven tesla (T) MR imaging is potentially promising for the morphologic evaluation of coronary arteries because of the increased signal-to-noise ratio compared to lower field strengths, in turn allowing improved spatial resolution, improved temporal resolution, or reduced scanning times. However, there are a large number of technical challenges, including the commercial 7 T systems not being equipped with homogeneous body radiofrequency coils, conservative specific absorption rate constraints, and magnified sample-induced amplitude of radiofrequency field inhomogeneity. In the present study, an initial attempt was made to address these challenges and to implement coronary MR angiography at 7 T. A single-element radiofrequency transmit and receive coil was designed and a 7 T specific imaging protocol was implemented, including significant changes in scout scanning, contrast generation, and navigator geometry compared to current protocols at 3 T. With this methodology, the first human coronary MR images were successfully obtained at 7 T, with both qualitative and quantitative findings being presented.

Original languageEnglish (US)
Pages (from-to)1379-1384
Number of pages6
JournalMagnetic resonance in medicine
Volume62
Issue number6
DOIs
StatePublished - Dec 2009

Keywords

  • 7 Tesla
  • Coronary
  • Human
  • In vivo
  • Magnetic resonance angiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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