Initial experience with the use of foetal/neonatal bovine acellular dermal collagen matrix (SurgiMend™) for tissue-expander breast reconstruction

Rika Ohkuma, Kate J. Buretta, Raja Mohan, Gedge D. Rosson, Ariel N. Rad

Research output: Contribution to journalArticlepeer-review

Abstract

Background Acellular dermal matrix (ADM) is commonly used in staged breast reconstruction using tissue expanders (TEs). The literature on human ADM has reported variable outcomes, and there is a paucity of data for xenogenic sources of ADM. The aim of this study is to evaluate the early complications, risk factors and outcomes using SurgiMend™ in staged breast reconstruction. Methods An Institutional Review Board (IRB)-approved, retrospective analysis of a single surgeon's experience was performed. From August 2009 to May 2011, 65 patients underwent staged breast reconstruction using 95 sheets of SurgiMend™. The nominal TE fill volume was 383 ± 83 cc (range 250-550), mean intra-operative fill volume was 148 ± 86 cc (range 0-350) and mean final fill volume was 413 ± 176 cc (range 100-800). The mean clinic follow-up time was 16.9 ± 8.7 months; mean age was 50.9 ± 11.7 years; and average body mass index (BMI) was 26.0 ± 5.5 kg m -2. Correlation with risk factors and clinical outcomes were analysed. Results The incidences of postoperative complications were: haematoma 3.2%, seroma 7.5% and re-operation due to infection 2.1%. Age, diabetes mellitus, and hypertension had a significant correlation with an increased overall complication rate. With respect to early complications, such as infection requiring re-operation, diabetes demonstrated a trend with an odds ratio of 11.69. Conclusion This study demonstrates that the use of SurgiMend™ is associated with low early complication rates and is well tolerated in staged breast reconstruction.

Original languageEnglish (US)
Pages (from-to)1195-1201
Number of pages7
JournalJournal of Plastic, Reconstructive and Aesthetic Surgery
Volume66
Issue number9
DOIs
StatePublished - Sep 1 2013

Keywords

  • Bovine acellular dermal matrix
  • Breast reconstruction
  • SurgiMend™

ASJC Scopus subject areas

  • Surgery

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