Initial experience with iv ketamine infusion for treatment of post sternotomy pain in a patient with a total artificial heart

Dermot P. Maher; Rusty Loyferman; Roya Yumul; Charles Louy

Initial experience with iv ketamine infusion for treatment of post sternotomy pain in a patient with a total artificial heart

Dermot P. Maher, Rusty Loyferman, Roya Yumul, Charles Louy

Research output: Contribution to journal › Article › peer-review

Abstract

The implantation of total artificial hearts (TAHs) via midline sternotomy for the treatment of severe biventricular cardiac dysfunction is associated with complex postoperative pain management. Ketamaine increases blood pressure by raising sympathetic outflow and cardiac ouput; however, ketamine is a direct vasodilator on isolated arterial tissues. In the setting of a TAH with a mechanically fixed cardiac output, a ketamine infusion for postoperative pain control has the potential to decrease blood pressure due to direct arterial vasodilation. We present the initial experience with a ketamine infusion in a patient with a TAH with minimal observed decreases in blood pressure and significantly improved postoperative pain.

Original language	English (US)
Pages (from-to)	E425-E428
Journal	Pain physician
Volume	18
Issue number	3
State	Published - Jan 1 2015
Externally published	Yes

Keywords

Hypotension
Ketamine
Mechanical circulation
Postoperative pain
Poststernotomy pain
Total artificial heart
Vasodilation

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Cite this

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AU - Louy, Charles

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N2 - The implantation of total artificial hearts (TAHs) via midline sternotomy for the treatment of severe biventricular cardiac dysfunction is associated with complex postoperative pain management. Ketamaine increases blood pressure by raising sympathetic outflow and cardiac ouput; however, ketamine is a direct vasodilator on isolated arterial tissues. In the setting of a TAH with a mechanically fixed cardiac output, a ketamine infusion for postoperative pain control has the potential to decrease blood pressure due to direct arterial vasodilation. We present the initial experience with a ketamine infusion in a patient with a TAH with minimal observed decreases in blood pressure and significantly improved postoperative pain.

AB - The implantation of total artificial hearts (TAHs) via midline sternotomy for the treatment of severe biventricular cardiac dysfunction is associated with complex postoperative pain management. Ketamaine increases blood pressure by raising sympathetic outflow and cardiac ouput; however, ketamine is a direct vasodilator on isolated arterial tissues. In the setting of a TAH with a mechanically fixed cardiac output, a ketamine infusion for postoperative pain control has the potential to decrease blood pressure due to direct arterial vasodilation. We present the initial experience with a ketamine infusion in a patient with a TAH with minimal observed decreases in blood pressure and significantly improved postoperative pain.

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KW - Mechanical circulation

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KW - Poststernotomy pain

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KW - Vasodilation

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Initial experience with iv ketamine infusion for treatment of post sternotomy pain in a patient with a total artificial heart

Abstract

Keywords

ASJC Scopus subject areas

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