Initial experience with a novel heat-exchanging catheter in neurosurgical patients

Anthony G. Doufas, Ozan Akça, Atul Barry, David A. Petrusca, M-Irfan Suleman, Nobutada Morioka, John J. Guarnaschelli, Daniel I. Sessler

Research output: Contribution to journalArticle

Abstract

Even mild hypothermia provides marked protection against cerebral ischemia in animal models. Hypothermia may be of therapeutic value during neurosurgical procedures. However, current cooling systems often fail to induce sufficient hypothermia before the dura is opened. Furthermore, they usually fail to restore normothermia by the end of surgery, thus delaying extubation. We evaluated a new internal heat-exchanging catheter. Eight ASA physical status II-IV patients (29-72 yr) undergoing craniotomy were enrolled. After the induction of general anesthesia, we introduced the SetPoint® catheter into the inferior vena cava via a femoral vein. The target core body temperature was 34°C-34.5°C. After reaching the target, core temperature was maintained until the dura was closed. Target core temperature was then set to 37.0°C, and the patient was rewarmed as quickly as possible. Seven patients had a tumor resection, and one had an aneurysm clipped. The core-cooling rate was 3.9°C ± 1.6°C/h, and the rewarming rate was 2.0°C ± 0.5°C/h; core temperature was 35.9°C ± 0.2°C by the end of surgery. Patients were subsequently kept normothermic for 3 h before the catheter was removed. No thrombus or other particulate material was identified on the extracted catheters. None of the patients suffered any complications that could be attributed to the SetPoint® system or thermal management.

Original languageEnglish (US)
Pages (from-to)1752-1756
Number of pages5
JournalAnesthesia and Analgesia
Volume95
Issue number6
StatePublished - Dec 1 2002
Externally publishedYes

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Catheters
Hot Temperature
Hypothermia
Temperature
Neurosurgical Procedures
Rewarming
Femoral Vein
Craniotomy
Inferior Vena Cava
Brain Ischemia
Body Temperature
General Anesthesia
Aneurysm
Thrombosis
Animal Models
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Doufas, A. G., Akça, O., Barry, A., Petrusca, D. A., Suleman, M-I., Morioka, N., ... Sessler, D. I. (2002). Initial experience with a novel heat-exchanging catheter in neurosurgical patients. Anesthesia and Analgesia, 95(6), 1752-1756.

Initial experience with a novel heat-exchanging catheter in neurosurgical patients. / Doufas, Anthony G.; Akça, Ozan; Barry, Atul; Petrusca, David A.; Suleman, M-Irfan; Morioka, Nobutada; Guarnaschelli, John J.; Sessler, Daniel I.

In: Anesthesia and Analgesia, Vol. 95, No. 6, 01.12.2002, p. 1752-1756.

Research output: Contribution to journalArticle

Doufas, AG, Akça, O, Barry, A, Petrusca, DA, Suleman, M-I, Morioka, N, Guarnaschelli, JJ & Sessler, DI 2002, 'Initial experience with a novel heat-exchanging catheter in neurosurgical patients', Anesthesia and Analgesia, vol. 95, no. 6, pp. 1752-1756.
Doufas AG, Akça O, Barry A, Petrusca DA, Suleman M-I, Morioka N et al. Initial experience with a novel heat-exchanging catheter in neurosurgical patients. Anesthesia and Analgesia. 2002 Dec 1;95(6):1752-1756.
Doufas, Anthony G. ; Akça, Ozan ; Barry, Atul ; Petrusca, David A. ; Suleman, M-Irfan ; Morioka, Nobutada ; Guarnaschelli, John J. ; Sessler, Daniel I. / Initial experience with a novel heat-exchanging catheter in neurosurgical patients. In: Anesthesia and Analgesia. 2002 ; Vol. 95, No. 6. pp. 1752-1756.
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