Inhibitors of poly(ADP-ribose) synthetase and use thereof to treat NMDA neurotoxicity

Research output: Contribution to journalArticlepeer-review

Abstract

Inhibitors of poly(ADP-ribose) synthetase can be used to prevent neurotoxicity mediated through N-methyl-D-aspartate (NMDA) receptors. Poly(ADP-ribose) synthetase inhibitors can be used therapeutically in the treatment of vascular stroke and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Huntington's disease.

Original languageEnglish (US)
Number of pages1
JournalBiotechnology Advances
Volume15
Issue number3-4
DOIs
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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