(1) The data presented demonstrate that Benemid in doses of 2 g per day per adult produced approximately 50% diminution in urinary 17-keto-steroids. This diminution was not exaggerated by increasing the dose of Benemid to 4 g per day. (2) Spectrophotometric studies showed that Benemid did not change the androsterone-dehydroisoandrosterone ratio of urinary 17-ketosteroids. (3) Urinary estrogens were diminished in one subject. In another subject this diminution was questionable. (4) Urinary 11-oxycorticosteroids (neutral reducing lipids) did not appear to be affected by Benemid.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Nov 1951|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)