Inhibition of tumor promotion by a biomimetic superoxide dismutase

Thomas W. Kensler; Donna M. Bush; Walter J. Kozumbo

Inhibition of tumor promotion by a biomimetic superoxide dismutase

Thomas W. Kensler, Donna M. Bush, Walter J. Kozumbo

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

A low molecular weight, lipophilic, copper coordination complex with Superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.

Original language	English (US)
Pages (from-to)	73-75
Number of pages	3
Journal	Science
Volume	221
Issue number	4605
State	Published - 1983

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@article{3d222780f79b42d3b6bba8aef48c6022,

title = "Inhibition of tumor promotion by a biomimetic superoxide dismutase",

abstract = "A low molecular weight, lipophilic, copper coordination complex with Superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.",

author = "Kensler, {Thomas W.} and Bush, {Donna M.} and Kozumbo, {Walter J.}",

year = "1983",

language = "English (US)",

volume = "221",

pages = "73--75",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4605",

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TY - JOUR

T1 - Inhibition of tumor promotion by a biomimetic superoxide dismutase

AU - Kensler, Thomas W.

AU - Bush, Donna M.

AU - Kozumbo, Walter J.

PY - 1983

Y1 - 1983

N2 - A low molecular weight, lipophilic, copper coordination complex with Superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.

AB - A low molecular weight, lipophilic, copper coordination complex with Superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.

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M3 - Article

AN - SCOPUS:37049186586

SN - 0036-8075

VL - 221

SP - 73

EP - 75

JO - Science

JF - Science

IS - 4605

ER -

Inhibition of tumor promotion by a biomimetic superoxide dismutase

Abstract

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