Inhibition of neovascularization by an extract derived from vitreous

Steven Brem, Ivan Preis, Robert Langer, Henry Brem, Judah Folkman, Arnall Patz

Research output: Contribution to journalArticlepeer-review

99 Scopus citations


An extract of the vitreous body, inhibited the growth of new blood vessels induced by tumors in the rabbit cornea. This extract was delivered by an inert, continuously releasing polymer. The average vessel growth rate in the region surrounding the polymer was 32% less in corneas containing the inhibitory substance than in control corneas.

Original languageEnglish (US)
Pages (from-to)323-325
Number of pages3
JournalAmerican journal of ophthalmology
Issue number3
StatePublished - Sep 1977
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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