Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a peltier-cooled sample stage

Christopher E. Von Seggern, Ben D. Gardner, Robert J. Cotter

Research output: Contribution to journalArticle

Abstract

Infrared atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used to analyze frozen samples generated using a Peltier-cooled sample stage. This allows for the analysis of samples in water without the addition of matrix, in near-native conditions, and with minimal loss of water due to evaporation. Analysis of frozen samples is extended to study peptides, carbohydrates, and glycolipids.

Original languageEnglish (US)
Pages (from-to)5887-5893
Number of pages7
JournalAnalytical Chemistry
Volume76
Issue number19
DOIs
StatePublished - Oct 1 2004

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Atmospheric pressure
Mass spectrometry
Ions
Infrared radiation
Water
Glycolipids
Mass spectrometers
Ionization
Desorption
Evaporation
Carbohydrates
Peptides
Lasers

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a peltier-cooled sample stage. / Von Seggern, Christopher E.; Gardner, Ben D.; Cotter, Robert J.

In: Analytical Chemistry, Vol. 76, No. 19, 01.10.2004, p. 5887-5893.

Research output: Contribution to journalArticle

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