TY - JOUR
T1 - Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
AU - Cresta, Fernando Betty
AU - Ma, Steven
AU - LaBree, Lauree D.
AU - McDonnell, Peter J.
PY - 2002
Y1 - 2002
N2 - Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon-fluoride excimer laser (VISX) with 160 mJ/ cm2 fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was α=0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01)and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: -0.55 (±0.88) and 0.97 (±0.79); -0.75 (±1.24) and 0.40 (±0.45);-1.21 (±2.55) and 0.75 (±0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.
AB - Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon-fluoride excimer laser (VISX) with 160 mJ/ cm2 fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was α=0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01)and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: -0.55 (±0.88) and 0.97 (±0.79); -0.75 (±1.24) and 0.40 (±0.45);-1.21 (±2.55) and 0.75 (±0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.
KW - Keratectomy photorefractive for excimer laser
KW - Myopia/surgery
KW - Racial stocks
KW - Refraction errors
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U2 - 10.1590/S0004-27492002000200014
DO - 10.1590/S0004-27492002000200014
M3 - Article
AN - SCOPUS:52649090255
SN - 0004-2749
VL - 65
SP - 235
EP - 238
JO - Arquivos brasileiros de oftalmologia
JF - Arquivos brasileiros de oftalmologia
IS - 2
ER -