Influence of patient race on the outcome of photorefractive keratectomy for myopia correction

Fernando Betty Cresta, Steven Ma, Lauree D. LaBree, Peter J McDonnell

Research output: Contribution to journalArticle

Abstract

Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon-fluoride excimer laser (VISX) with 160 mJ/ cm 2 fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was α=0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01)and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: -0.55 (±0.88) and 0.97 (±0.79); -0.75 (±1.24) and 0.40 (±0.45);-1.21 (±2.55) and 0.75 (±0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.

Original languageEnglish (US)
Pages (from-to)235-238
Number of pages4
JournalArquivos Brasileiros de Oftalmologia
Volume65
Issue number2
StatePublished - 2002
Externally publishedYes

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Photorefractive Keratectomy
Myopia
Visual Acuity
Hispanic Americans
Excimer Lasers
Astigmatism
Laser Therapy

Keywords

  • Keratectomy photorefractive for excimer laser
  • Myopia/surgery
  • Racial stocks
  • Refraction errors

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Influence of patient race on the outcome of photorefractive keratectomy for myopia correction. / Cresta, Fernando Betty; Ma, Steven; LaBree, Lauree D.; McDonnell, Peter J.

In: Arquivos Brasileiros de Oftalmologia, Vol. 65, No. 2, 2002, p. 235-238.

Research output: Contribution to journalArticle

Cresta, Fernando Betty ; Ma, Steven ; LaBree, Lauree D. ; McDonnell, Peter J. / Influence of patient race on the outcome of photorefractive keratectomy for myopia correction. In: Arquivos Brasileiros de Oftalmologia. 2002 ; Vol. 65, No. 2. pp. 235-238.
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N2 - Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon-fluoride excimer laser (VISX) with 160 mJ/ cm 2 fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was α=0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01)and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: -0.55 (±0.88) and 0.97 (±0.79); -0.75 (±1.24) and 0.40 (±0.45);-1.21 (±2.55) and 0.75 (±0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.

AB - Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon-fluoride excimer laser (VISX) with 160 mJ/ cm 2 fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was α=0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01)and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: -0.55 (±0.88) and 0.97 (±0.79); -0.75 (±1.24) and 0.40 (±0.45);-1.21 (±2.55) and 0.75 (±0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.

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