Influence of major histocompatibility haplotype on autoimmune disease varies in different inbred families of chickens

L. D. Bacon, N. R. Rose

Research output: Contribution to journalArticle

Abstract

Three partially inbred substrains of obese strain chickens were studied for the spontaneous development of autoimmune thyroiditis. The influence of the major histocompatibility complex (B haplotype) was marked in 1, less marked but still significant in a 2nd, and barely detectable and transient in a third substrain. These differences in the effect of B haplotype may be due to the overriding action of genes other than those within the B haplotype.

Original languageEnglish (US)
Pages (from-to)1435-1437
Number of pages3
JournalProceedings of the National Academy of Sciences of the United States of America
Volume76
Issue number3
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Influence of major histocompatibility haplotype on autoimmune disease varies in different inbred families of chickens'. Together they form a unique fingerprint.

  • Cite this