Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults

Mario Estévez-Báez, Claudia Carricarte-Naranjo, Javier Denis Jas-García, Evelyn Rodríguez-Ríos, Calixto Machado, Julio Montes-Brown, Gerry Leisman, Adam Schiavi, Andrés Machado-García, Claudia Sánchez Luaces, Eduardo Arrufat Pié

Research output: Contribution to journalArticle

Abstract

Key autonomic functions are in continuous development during adolescence which can be assessed using the heart rate variability (HRV). However, the influence of different demographic and physiological factors on HRV indices has not been fully explored in adolescents. In this study we aimed to assess the effect of age, gender, and heart rate on HRV indices in two age groups of healthy adolescents (age ranges, 13-16 and 17-20 years) and two groups of healthy young adults (21-24 and 25-30 years). We addressed the issue using 5-min ECG recordings performed in the sitting position in 255 male and female participants. Time, frequency, and informational domains of HRV were calculated. Changes in HRV indices were assessed using a multiple linear regression model to adjust for the effects of heart rate, age, and gender. We found that heart rate produced more significant effects on HRV indices than age or gender. There was a progressive reduction in HRV with increasing age. Sympathetic influence increased with age and parasympathetic influence progressively decreased with age. The influence of gender was manifest only in younger adolescents and young adults. In conclusion, age, gender, and particularly heart rate have a substantial influence on HRV indices, which ought to be considered to avoid biases in the study of the autonomic nervous system development. The lack of the gender-related effects on HRV indices in late adolescence could be related to non-completely achieved maturity of the autonomic mechanisms, which deserves further exploration.

Original languageEnglish (US)
Pages (from-to)19-33
Number of pages15
JournalAdvances in experimental medicine and biology
Volume1133
DOIs
StatePublished - Jan 1 2019

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Young Adult
Heart Rate
Linear Models
Autonomic Nervous System
Neurology
Electrocardiography
Posture
Linear regression
Age Groups
Demography

Keywords

  • Adolescents
  • Age
  • Autonomic nervous system
  • Gender
  • Heart rate variability
  • Power spectral analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Estévez-Báez, M., Carricarte-Naranjo, C., Jas-García, J. D., Rodríguez-Ríos, E., Machado, C., Montes-Brown, J., ... Pié, E. A. (2019). Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults. Advances in experimental medicine and biology, 1133, 19-33. https://doi.org/10.1007/5584_2018_292

Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults. / Estévez-Báez, Mario; Carricarte-Naranjo, Claudia; Jas-García, Javier Denis; Rodríguez-Ríos, Evelyn; Machado, Calixto; Montes-Brown, Julio; Leisman, Gerry; Schiavi, Adam; Machado-García, Andrés; Luaces, Claudia Sánchez; Pié, Eduardo Arrufat.

In: Advances in experimental medicine and biology, Vol. 1133, 01.01.2019, p. 19-33.

Research output: Contribution to journalArticle

Estévez-Báez, M, Carricarte-Naranjo, C, Jas-García, JD, Rodríguez-Ríos, E, Machado, C, Montes-Brown, J, Leisman, G, Schiavi, A, Machado-García, A, Luaces, CS & Pié, EA 2019, 'Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults', Advances in experimental medicine and biology, vol. 1133, pp. 19-33. https://doi.org/10.1007/5584_2018_292
Estévez-Báez M, Carricarte-Naranjo C, Jas-García JD, Rodríguez-Ríos E, Machado C, Montes-Brown J et al. Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults. Advances in experimental medicine and biology. 2019 Jan 1;1133:19-33. https://doi.org/10.1007/5584_2018_292
Estévez-Báez, Mario ; Carricarte-Naranjo, Claudia ; Jas-García, Javier Denis ; Rodríguez-Ríos, Evelyn ; Machado, Calixto ; Montes-Brown, Julio ; Leisman, Gerry ; Schiavi, Adam ; Machado-García, Andrés ; Luaces, Claudia Sánchez ; Pié, Eduardo Arrufat. / Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults. In: Advances in experimental medicine and biology. 2019 ; Vol. 1133. pp. 19-33.
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