Influence of depression and age on selected cognitive functions

D. A. King, E. D. Caine, C. Cox

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


In order to test for possible interaction between the effects of age and the effects of depression, 45 patients with unipolar major depression and 118 normal controls ranging in age from 23 to 87 years completed tests of language, verbal and visual memory, copying, and complex psychomotor function. Biphasic regression analyses suggested more accelerated declines with age in the depressed group on tests of naming and complex psychomotor function. However, there were parallel age effects in depressives and controls on tests of verbal and visual memory, and copying. These results are discussed in terms of cognitive and neurobiologic processes that may underlie an interactive relationship between the effects of depression and the effects of age.

Original languageEnglish (US)
Pages (from-to)443-453
Number of pages11
JournalClinical Neuropsychologist
Issue number4
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Clinical Psychology
  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health


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