TY - JOUR
T1 - Influence of depression and age on selected cognitive functions
AU - King, D. A.
AU - Caine, E. D.
AU - Cox, C.
N1 - Funding Information:
There are several ways in which age and depression may have combined effects on cognition. One possibility is that age and depression have independent This study was supported by NIMH grants MH-42141 and MH-40381. The authors thank Heather Booth, Jane Gogan, Beth Palermo, Kurt Olsen, and Hilda Satran for assistance with data collection and/or management, and Janet Werkheiser for her help in preparing this manuscript. A subsidiary set of analyses concerning the influence of covariates on the dependent variables is available from the authors. Address for reprints and correspondence: Deborah A. King, Ph.D., Associate Professor of Psychiatry (Psychology), University of Rochester, Strong Memorial Hospital, 300 Crittenden Blvd., Rochester, NY 14642,
PY - 1993
Y1 - 1993
N2 - In order to test for possible interaction between the effects of age and the effects of depression, 45 patients with unipolar major depression and 118 normal controls ranging in age from 23 to 87 years completed tests of language, verbal and visual memory, copying, and complex psychomotor function. Biphasic regression analyses suggested more accelerated declines with age in the depressed group on tests of naming and complex psychomotor function. However, there were parallel age effects in depressives and controls on tests of verbal and visual memory, and copying. These results are discussed in terms of cognitive and neurobiologic processes that may underlie an interactive relationship between the effects of depression and the effects of age.
AB - In order to test for possible interaction between the effects of age and the effects of depression, 45 patients with unipolar major depression and 118 normal controls ranging in age from 23 to 87 years completed tests of language, verbal and visual memory, copying, and complex psychomotor function. Biphasic regression analyses suggested more accelerated declines with age in the depressed group on tests of naming and complex psychomotor function. However, there were parallel age effects in depressives and controls on tests of verbal and visual memory, and copying. These results are discussed in terms of cognitive and neurobiologic processes that may underlie an interactive relationship between the effects of depression and the effects of age.
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U2 - 10.1080/13854049308401534
DO - 10.1080/13854049308401534
M3 - Article
AN - SCOPUS:0027731026
VL - 7
SP - 443
EP - 453
JO - Clinical Neuropsychologist
JF - Clinical Neuropsychologist
SN - 1385-4046
IS - 4
ER -