Abstract
Despite accumulating evidence that inflammation may affect the development of prostate cancer, responsible causes of intraprostatic inflammation remain elusive. This review presents epidemiologic literature on infections, particularly sexually transmitted and other ascending urogenital infections, as possible causes of intraprostatic inflammation and/or prostate cancer. Study results are interpreted in light of the inflammatory and carcinogenic potential of each infectious agent, as well as the design, analysis, and historical and cultural context of each epidemiologic study. Such findings motivate additional investigation of traditionally explored organisms, such as Neisseria gonorrhoeae, and more recently explored organisms, such as Propionibacterium acnes, with careful consideration of their biology and epidemiology, as well as the design and analysis of epidemiologic studies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 243-249 |
| Number of pages | 7 |
| Journal | Current Urology Reports |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 2008 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Urology
Cite this
Inflammation and prostate cancer : A focus on infections. / Sutcliffe, Siobhan; Platz, Elizabeth A.
In: Current Urology Reports, Vol. 9, No. 3, 05.2008, p. 243-249.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Inflammation and prostate cancer
T2 - A focus on infections
AU - Sutcliffe, Siobhan
AU - Platz, Elizabeth A
PY - 2008/5
Y1 - 2008/5
N2 - Despite accumulating evidence that inflammation may affect the development of prostate cancer, responsible causes of intraprostatic inflammation remain elusive. This review presents epidemiologic literature on infections, particularly sexually transmitted and other ascending urogenital infections, as possible causes of intraprostatic inflammation and/or prostate cancer. Study results are interpreted in light of the inflammatory and carcinogenic potential of each infectious agent, as well as the design, analysis, and historical and cultural context of each epidemiologic study. Such findings motivate additional investigation of traditionally explored organisms, such as Neisseria gonorrhoeae, and more recently explored organisms, such as Propionibacterium acnes, with careful consideration of their biology and epidemiology, as well as the design and analysis of epidemiologic studies.
AB - Despite accumulating evidence that inflammation may affect the development of prostate cancer, responsible causes of intraprostatic inflammation remain elusive. This review presents epidemiologic literature on infections, particularly sexually transmitted and other ascending urogenital infections, as possible causes of intraprostatic inflammation and/or prostate cancer. Study results are interpreted in light of the inflammatory and carcinogenic potential of each infectious agent, as well as the design, analysis, and historical and cultural context of each epidemiologic study. Such findings motivate additional investigation of traditionally explored organisms, such as Neisseria gonorrhoeae, and more recently explored organisms, such as Propionibacterium acnes, with careful consideration of their biology and epidemiology, as well as the design and analysis of epidemiologic studies.
UR - http://www.scopus.com/inward/record.url?scp=44449101570&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44449101570&partnerID=8YFLogxK
U2 - 10.1007/s11934-008-0042-z
DO - 10.1007/s11934-008-0042-z
M3 - Article
VL - 9
SP - 243
EP - 249
JO - Current Urology Reports
JF - Current Urology Reports
SN - 1527-2737
IS - 3
ER -