Infectious Diseases (ID) learning unit: How rapidly to evaluate for active tuberculosis disease in low-prevalence settings

Research output: Contribution to journalArticle

Abstract

With declining tuberculosis (TB) incidence in low-prevalence settings, many clinicians are likely unaware that the approach to diagnosing active TB is evolving with newer technologies. Rapid molecular assays are commercially available, and more are likely to enter the market in the coming years. These tests, such as the Xpert MTB/RIF, which can detect TB and drug-resistance in 2 hours, are increasingly used in settings with higher TB prevalence; however, uptake has been slower in low-prevalence settings. Newer algorithms incorporating rapid TB diagnostics have the ability to alter current clinical and infection control practice patterns. In this learning unit, we review current and newly available tests for the detection of active TB disease and their usage in low-prevalence settings.

Original languageEnglish (US)
Article numberofw058
JournalOpen Forum Infectious Diseases
Volume3
Issue number2
DOIs
StatePublished - Apr 1 2016

Keywords

  • Diagnosis
  • Nucleic acid amplification tests
  • Tuberculosis

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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