Infectious crystalline keratopathy with ring opacity

J. M. McDonnell, David Gritz, D. Hwang, Peter J McDonnell

Research output: Contribution to journalArticle

Abstract

A 41-year-old physician was treated for 3 months with antiviral medications, antibiotics, and steroids for presumed herpetic keratitis. When seen by us, an annular infiltrate was observed, along with crystalline-like opacities in the superficial one third of the stroma. Cultures of scrapings and of subsequent biopsies were positive for Streptococcus mitis of the viridans group; histopathology demonstrated large aggregates of cocci between the stroma lamellae. Tapering of topical corticosteroids and treatment with topical penicillin resulted in resolution of the infiltrates. The clinical appearance and findings in this patient suggest that infectious crystalline keratitis can produce an annular infiltrate. Injection of the organism into rabbit corneas produced a crystalline infiltrate, but no annular opacity was observed. Corticosteroids altered the clinical and histopathologic appearance of the lesions in rabbits.

Original languageEnglish (US)
Pages (from-to)479-483
Number of pages5
JournalCornea
Volume11
Issue number5
StatePublished - 1992
Externally publishedYes

Fingerprint

Adrenal Cortex Hormones
Streptococcus mitis
Viridans Streptococci
Rabbits
Herpetic Keratitis
Keratitis
Penicillins
Cornea
Antiviral Agents
Steroids
Anti-Bacterial Agents
Physicians
Biopsy
Injections
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Infectious crystalline keratopathy with ring opacity. / McDonnell, J. M.; Gritz, David; Hwang, D.; McDonnell, Peter J.

In: Cornea, Vol. 11, No. 5, 1992, p. 479-483.

Research output: Contribution to journalArticle

McDonnell, JM, Gritz, D, Hwang, D & McDonnell, PJ 1992, 'Infectious crystalline keratopathy with ring opacity', Cornea, vol. 11, no. 5, pp. 479-483.
McDonnell, J. M. ; Gritz, David ; Hwang, D. ; McDonnell, Peter J. / Infectious crystalline keratopathy with ring opacity. In: Cornea. 1992 ; Vol. 11, No. 5. pp. 479-483.
@article{b0a4b46e228d4545ba145d6852d90a3d,
title = "Infectious crystalline keratopathy with ring opacity",
abstract = "A 41-year-old physician was treated for 3 months with antiviral medications, antibiotics, and steroids for presumed herpetic keratitis. When seen by us, an annular infiltrate was observed, along with crystalline-like opacities in the superficial one third of the stroma. Cultures of scrapings and of subsequent biopsies were positive for Streptococcus mitis of the viridans group; histopathology demonstrated large aggregates of cocci between the stroma lamellae. Tapering of topical corticosteroids and treatment with topical penicillin resulted in resolution of the infiltrates. The clinical appearance and findings in this patient suggest that infectious crystalline keratitis can produce an annular infiltrate. Injection of the organism into rabbit corneas produced a crystalline infiltrate, but no annular opacity was observed. Corticosteroids altered the clinical and histopathologic appearance of the lesions in rabbits.",
author = "McDonnell, {J. M.} and David Gritz and D. Hwang and McDonnell, {Peter J}",
year = "1992",
language = "English (US)",
volume = "11",
pages = "479--483",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Infectious crystalline keratopathy with ring opacity

AU - McDonnell, J. M.

AU - Gritz, David

AU - Hwang, D.

AU - McDonnell, Peter J

PY - 1992

Y1 - 1992

N2 - A 41-year-old physician was treated for 3 months with antiviral medications, antibiotics, and steroids for presumed herpetic keratitis. When seen by us, an annular infiltrate was observed, along with crystalline-like opacities in the superficial one third of the stroma. Cultures of scrapings and of subsequent biopsies were positive for Streptococcus mitis of the viridans group; histopathology demonstrated large aggregates of cocci between the stroma lamellae. Tapering of topical corticosteroids and treatment with topical penicillin resulted in resolution of the infiltrates. The clinical appearance and findings in this patient suggest that infectious crystalline keratitis can produce an annular infiltrate. Injection of the organism into rabbit corneas produced a crystalline infiltrate, but no annular opacity was observed. Corticosteroids altered the clinical and histopathologic appearance of the lesions in rabbits.

AB - A 41-year-old physician was treated for 3 months with antiviral medications, antibiotics, and steroids for presumed herpetic keratitis. When seen by us, an annular infiltrate was observed, along with crystalline-like opacities in the superficial one third of the stroma. Cultures of scrapings and of subsequent biopsies were positive for Streptococcus mitis of the viridans group; histopathology demonstrated large aggregates of cocci between the stroma lamellae. Tapering of topical corticosteroids and treatment with topical penicillin resulted in resolution of the infiltrates. The clinical appearance and findings in this patient suggest that infectious crystalline keratitis can produce an annular infiltrate. Injection of the organism into rabbit corneas produced a crystalline infiltrate, but no annular opacity was observed. Corticosteroids altered the clinical and histopathologic appearance of the lesions in rabbits.

UR - http://www.scopus.com/inward/record.url?scp=0026761406&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026761406&partnerID=8YFLogxK

M3 - Article

VL - 11

SP - 479

EP - 483

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 5

ER -