Infectious complications of blood transfusion

Evan Bloch, Cyril Jacquot, Beth H. Shaz

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Consequent to refined donor selection and laboratory screening, blood transfusion in the United States is remarkably safe. Nonetheless, emerging and reemerging pathogens may pose risk to the blood supply, underscoring the need for ongoing vigilance and development of innovative strategies to mitigate infectious risk. The following chapter is intended to provide a broad overview of the infectious complications of blood transfusion. This includes a description of the major transfusion transmitted pathogens, associated preventative strategies in use (donor risk-based deferral and donor and product laboratory testing), in addition to practical considerations surrounding how one responds to a suspected and/or confirmed transfusion transmitted infection (i.e., quarantine, look-back, and notification).

Original languageEnglish (US)
Title of host publicationTransfusion Medicine, Apheresis, and Hemostasis
Subtitle of host publicationReview Questions and Case Studies
PublisherElsevier
Pages241-266
Number of pages26
ISBN (Electronic)9780128039991
ISBN (Print)9780128040300
DOIs
StatePublished - Sep 20 2017

Keywords

  • Bacteria
  • Laboratory testing
  • Look-back and deferral
  • Parasites
  • Prions
  • Transfusion transmitted infections
  • Viruses

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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  • Cite this

    Bloch, E., Jacquot, C., & Shaz, B. H. (2017). Infectious complications of blood transfusion. In Transfusion Medicine, Apheresis, and Hemostasis: Review Questions and Case Studies (pp. 241-266). Elsevier. https://doi.org/10.1016/B978-0-12-803999-1.00011-0