INFANTILE GASTROENTERITIS ASSOCIATED WITH EXCRETION OF PESTIVIRUS ANTIGENS

Robert H Yolken, Flora Leister, Janae Almeido-Hill, Edward Dubovi, Raymond Reid, Mathuram Santosham

Research output: Contribution to journalArticle

Abstract

Faeces from children under 2 years old who had gastroenteritis that could not be attributed to recognised enteric pathogens were examined with a monoclonal-antibody-based immunoassay for Pestivirus antigens. Such antigens were detected in 30 of 128 episodes of gastroenteritis. Children without diarrhoeal disease and children infected with rotaviruses had little evidence of Pestivirus infection (faeces positive in 1 of 28 and 1 of 31, respectively). The diarrhoeal disease in children excreting Pestivirus antigens resembled that in other children except that it was more commonly associated with signs and symptoms of respiratory inflammation.

Original languageEnglish (US)
Pages (from-to)517-520
Number of pages4
JournalThe Lancet
Volume333
Issue number8637
DOIs
StatePublished - Mar 11 1989

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Pestivirus
Gastroenteritis
Antigens
Feces
Pestivirus Infections
Respiratory Signs and Symptoms
Rotavirus
Immunoassay
Monoclonal Antibodies
Inflammation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

INFANTILE GASTROENTERITIS ASSOCIATED WITH EXCRETION OF PESTIVIRUS ANTIGENS. / Yolken, Robert H; Leister, Flora; Almeido-Hill, Janae; Dubovi, Edward; Reid, Raymond; Santosham, Mathuram.

In: The Lancet, Vol. 333, No. 8637, 11.03.1989, p. 517-520.

Research output: Contribution to journalArticle

Yolken, Robert H ; Leister, Flora ; Almeido-Hill, Janae ; Dubovi, Edward ; Reid, Raymond ; Santosham, Mathuram. / INFANTILE GASTROENTERITIS ASSOCIATED WITH EXCRETION OF PESTIVIRUS ANTIGENS. In: The Lancet. 1989 ; Vol. 333, No. 8637. pp. 517-520.
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